Long-term ambient ozone exposure and incident cardiovascular diseases: National cohort evidence in China

被引：9

作者：

Zhu, Lifeng ^{[1
]}

Fang, Jiaying ^{[2
]}

Yao, Yao ^{[3
]}

Yang, Zhiming ^{[4
]}

Wu, Jing ^{[3
]}

Ma, Zongwei ^{[5
]}

Liu, Riyang ^{[5
]}

Zhan, Yu ^{[6
]}

Ding, Zan ^{[7
]}

Zhang, Yunquan ^{[1
,8
]}

机构：

[1] Wuhan Univ Sci & Technol, Inst Social Dev & Hlth Management, Sch Publ Hlth, Hubei Prov Key Lab Occupat Hazard Identificat & Co, Wuhan 430065, Peoples R China

[2] Huadu Dist Peoples Hosp Guangzhou, Guangzhou 510800, Peoples R China

[3] Peking Univ, China Ctr Hlth Dev Studies, Beijing 100871, Peoples R China

[4] Univ Sci & Technol Beijing, Sch Econ & Management, Beijing 100083, Peoples R China

[5] Nanjing Univ, Sch Environm, State Key Lab Pollut Control & Resource Reuse, Nanjing 210023, Peoples R China

[6] Sichuan Univ, Dept Environm Sci & Engn, Chengdu 610065, Peoples R China

[7] Baoan Cent Hosp Shenzhen, Shenzhen 518102, Peoples R China

[8] Wuhan Univ Sci & Technol, Sch Publ Hlth, Wuhan 430065, Peoples R China

来源：

JOURNAL OF HAZARDOUS MATERIALS | 2024年 / 471卷

关键词：

Ozone; Long-term exposure; Cardiovascular disease; Attributable burden; China; AIR-POLLUTION; GLOBAL BURDEN; MORTALITY; PREVALENCE; TRENDS; PM2.5;

D O I：

10.1016/j.jhazmat.2024.134158

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Background: Long-term ozone (O3) exposure has been associated with cardiovascular disease (CVD) mortality in mounting cohort evidence, yet its relationship with incident CVD was poorly understood, especially in low- and middle-income countries (LMICs) experiencing high ambient air pollution. Methods: We carried out a nationwide perspective cohort study from 2010 through 2018 by dynamically enrolling 36948 participants across Chinese mainland. Warm-season (April-September) O3 concentrations were estimated using satellite-based machine-learning models with national coverage. Cox proportional hazards model with time-varying exposures was employed to evaluate the association of long-term O3 exposure with incident CVD (overall CVD, hypertension, stroke, and coronary heart disease [CHD]). Assuming causality, a

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页数：11

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