mTORc2 in the distal convoluted tubule (DCT) stimulates renal K+ excretion by inhibiting basolateral Kir4.1/Kir5.1 and Na-Cr- cotransporter (NCC) during increasing dietary K+ intake

被引：0
|
作者：
Lin, Daohong
Wang, Wenhui
Duan, Xinpeng
机构：
来源：
PHYSIOLOGY | 2024年 / 39卷
关键词：
D O I：
10.1152/physiol.2024.39.S1.486
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
引用
收藏
页数：2
相关论文
共 18 条
  • [11] Biphasic effect of PGF2a on the basolateral 40 pS K channel (a heterotetramer of Kir4.1 and Kir5.1) in the early distal convoluted tubule (DCT1)
    Wang, Lijun
    Zhang, Chengbiao
    Su, Xiaotong
    Wang, Wen-Hui
    FASEB JOURNAL, 2014, 28 (01):
  • [12] Down-regulation of Kir4.1 eliminates the basolateral K conductance in the distal convoluted tubule (DCT) and inhibits NCC activity
    Su, Xiao-Tong
    Wang, Ming-Xiao
    Wu, Peng
    McCormick, James A.
    Ellison, David E.
    Wang, Wen-Hui
    FASEB JOURNAL, 2016, 30
  • [13] AT2R is involved in mediating the effect of high dietary K (HK) intake on basolateral Kir4.1 in the distal convoluted tubule (DCT)
    Wu, Peng
    Gao, Zhongxiuzi
    Wang, Mingxiao
    Su, Xiao-Tong
    Wang, Lijun
    Wang, Wen-Hui
    FASEB JOURNAL, 2016, 30
  • [14] Kir4.1/Kir5.1 channel forms the major K+ channel in the basolateral membrane of mouse renal collecting duct principal cells
    Lachheb, Sahran
    Cluzeaud, Francoise
    Bens, Marcelle
    Genete, Mathieu
    Hibino, Hiroshi
    Lourdel, Stephane
    Kurachi, Yoshihisa
    Vandewalle, Alain
    Teulon, Jacques
    Paulais, Marc
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2008, 294 (06) : F1398 - F1407
  • [15] Immunolocalization of an inwardly rectifying K+ channel, K-AB-2 (Kir4.1), in the basolateral membrane of renal distal tubular epithelia
    Ito, M
    Inanobe, A
    Horio, Y
    Hibino, H
    Isomoto, S
    Ito, H
    Mori, K
    Tonosaki, A
    Tomoike, H
    Kurachi, Y
    FEBS LETTERS, 1996, 388 (01) : 11 - 15
  • [16] Deletion of NEDD4-2 Abolishes the Inhibitory Effect of High Sodium (HS) Intake on the Basolateral Kir4.1/Kir5.1 of the DCT and Thiazide-Sensitive Na-Cl Cotransport (NCC)
    Zhang, Dandan
    Duan, Xin-Peng
    Wu, Peng
    Xiao, Yu
    Gao, Zhong-Xiuzi
    Wang, Wen-Hui
    Lin, Dao-Hong
    FASEB JOURNAL, 2020, 34
  • [17] Activation of Kir4.1 is essential for switching the function of DCT2 to DCT1 by Stimulating NCC and inhibiting ROMK/ENaC during dietary K restriction
    Wang, Mingxiao
    Su, Xiao-Tong
    Wu, Peng
    Lin, Dao-Hong
    McCormick, James A.
    Ellison, David E.
    Wang, Wen-Hui
    FASEB JOURNAL, 2016, 30
  • [18] AT2R (Angiotensin II Type 2 Receptor)-Mediated Regulation of NCC (Na-Cl Cotransporter) and Renal K Excretion Depends on the K Channel, Kir4.1
    Wu, Peng
    Gao, Zhong-Xiuzi
    Duan, Xin-Peng
    Su, Xiao-Tong
    Wang, Ming-Xiao
    Lin, Dao-Hong
    Gu, Ruimin
    Wang, Wen-Hui
    HYPERTENSION, 2018, 71 (04) : 622 - 630
12