The emerging role of the gut virome in necrotizing enterocolitis

被引：0

作者：

Yi, Cong ^{[1
]}

Chen, Jia ^{[1
]}

She, Xiang ^{[1
]}

机构：

[1] Univ Elect Sci & Technol China, Mianyang Cent Hosp, Sch Med, Dept Pediat, Mianyang 621000, Peoples R China

来源：

HELIYON | 2024年 / 10卷 / 09期

关键词：

Gut virome; Necrotizing enterocolitis; Therapy; INVASIVE ESCHERICHIA-COLI; ENTERIC VIRUSES; DYNAMICS; OUTBREAK; DISEASE; TWINS;

D O I：

10.1016/j.heliyon.2024.e30496

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates, particularly preterm infants. Many factors can lead to NEC, but microbial dysbiosis is one of the most important risk factors that can induce this disease. Given the major role of the gut virome in shaping bacterial homeostasis, virome research is a fledgling but rapidly evolving area in the field of microbiome that is increasingly connected to human diseases, including NEC. This review provides an overview of the development of the gut virome in newborns, discusses its emerging role in NEC, and explores promising therapeutic applications, including phage therapy and fecal virome transplantation.

引用

页数：6

共 80 条

[1] Detection of astrovirus in premature infants with necrotizing enterocolitis [J].

Bagci, Soyhan ;

Eis-Huebinger, Anna M. ;

Franz, Axel R. ;

Bierbaum, Gabriele ;

Heep, Axel ;

Schildgen, Oliver ;

Bartmann, Peter ;

Kupfer, Bernd ;

Mueller, Andreas .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2008, 27 (04) :347-350

[2] Echovirus type 22 outbreak associated with gastro-intestinal disease in a neonatal intensive care unit [J].

Birenbaum, E ;

Handsher, R ;

Kuint, J ;

Dagan, R ;

Raichman, B ;

Mendelson, E ;

Linder, N .

AMERICAN JOURNAL OF PERINATOLOGY, 1997, 14 (08) :469-473

[3] Evolution in fecal bacterial/viral composition in infants of two central African countries (Gabon and Republic of the Congo) during their first month of life [J].

Brazier, Lionel ;

Elguero, Eric ;

Koumavor, Claudine Kombila ;

Renaud, Nicolas ;

Prugnolle, Franck ;

Thomas, Frederic ;

Ategbo, Simon ;

Engoba, Moyen ;

Obengui ;

Leroy, Eric M. ;

Durand, Patrick ;

Renaud, Francois ;

Becquart, Pierre .

PLOS ONE, 2017, 12 (10)

[4] Metagenomic analyses of an uncultured viral community from human feces [J].

Breitbart, M ;

Hewson, I ;

Felts, B ;

Mahaffy, JM ;

Nulton, J ;

Salamon, P ;

Rohwer, F .

JOURNAL OF BACTERIOLOGY, 2003, 185 (20) :6220-6223

[5] Viral diversity and dynamics in an infant gut [J].

Breitbart, Mya ;

Haynes, Matthew ;

Kelley, Scott ;

Angly, Florent ;

Edwards, Robert A. ;

Felts, Ben ;

Mahaffy, Joseph M. ;

Mueller, Jennifer ;

Nulton, James ;

Rayhawk, Steve ;

Rodriguez-Brito, Beltran ;

Salamon, Peter ;

Rohwer, Forest .

RESEARCH IN MICROBIOLOGY, 2008, 159 (05) :367-373

[6] Fecal filtrate transplantation protects against necrotizing enterocolitis [J].

Brunse, Anders ;

Deng, Ling ;

Pan, Xiaoyu ;

Hui, Yan ;

Castro-Mejia, Josue L. ;

Kot, Witold ;

Nguyen, Duc Ninh ;

Secher, Jan Bojsen-Moller ;

Nielsen, Dennis Sandris ;

Thymann, Thomas .

ISME JOURNAL, 2022, 16 (03) :686-694

[7] Effect of fecal microbiota transplantation route of administration on gut colonization and host response in preterm pigs [J].

Brunse, Anders ;

Martin, Lena ;

Rasmussen, Torben Solbeck ;

Christensen, Lars ;

Cilieborg, Malene Skovsted ;

Wiese, Maria ;

Khakimov, Bekzod ;

Pieper, Robert ;

Nielsen, Dennis Sandris ;

Sangild, Per Torp ;

Thymann, Thomas .

ISME JOURNAL, 2019, 13 (03) :720-733

[8] Assembly of the virome in newborn human infants [J].

Bushman, Frederic ;

Liang, Guanxiang .

CURRENT OPINION IN VIROLOGY, 2021, 48 :17-22

[9] The association between enteric viruses and necrotizing enterocolitis [J].

Cheng, Chen ;

He, Yu ;

Xiao, Sa ;

Ai, Qing ;

Yu, Jialin .

EUROPEAN JOURNAL OF PEDIATRICS, 2021, 180 (01) :225-232

[10] Whole-Virome Analysis Sheds Light on Viral Dark Matter in Inflammatory Bowel Disease [J].

Clooney, Adam G. ;

Sutton, Thomas D. S. ;

Shkoporov, Andrey N. ;

Holohan, Ross K. ;

Daly, Karen M. ;

O'Regan, Orla ;

Ryan, Feargal J. ;

Draper, Lorraine A. ;

Plevy, Scott E. ;

Ross, R. Paul ;

Hill, Colin .

CELL HOST & MICROBE, 2019, 26 (06) :764-+

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