A case report of leukemoid reaction in a child with severe diabetic ketoacidosis (DKA) and cerebral edema: When rarity and complexity meet

被引：0

作者：

Alfraij, Abdulla ^{[1
,3
]}

Al-Enazi, Naser ^{[2
]}

机构：

[1] Gen Ahmadi Hosp KOC, Dept Pediat, Pediat Intens Care Unit, Ahmadi, Kuwait

[2] Gen Ahmadi Hosp KOC, Dept Pediat, Pediat Endocrinologist & Diabetologist, Ahmadi, Kuwait

[3] Gen Ahmadi Hosp KOC, Dept Pediat, POB 9758, Ahmadi 61008, Kuwait

来源：

CLINICAL CASE REPORTS | 2024年 / 12卷 / 06期

关键词：

cerebral edema; diabetic ketoacidosis; leukemoid reaction; pediatric; RISK-FACTORS;

D O I：

10.1002/ccr3.9017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The combination of diabetic ketoacidosis (DKA), cerebral edema, and leukemoid reaction in pediatrics has never been reported before in the literature. It may lead to significant morbidity and high mortality. Here, we report a case of DKA-induced cerebral edema associated with severe leukocytosis (WBC 98 x 10(9)/L), which had many challenges in fluid therapy.

引用

页数：5

共 16 条

[1] Sepsis-induced Hyperleukocytosis in a Preterm
Alatassi, Emad U.
Sukkar, Marah
Garrada, Fadi N.
[J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2019, 11 (09)
[2] Brain injury in children with diabetic ketoacidosis: Review of the literature and a proposed pathophysiologic pathway for the development of cerebral edema
Azova, Svetlana
Rapaport, Robert
Wolfsdorf, Joseph
[J]. PEDIATRIC DIABETES, 2021, 22 (02) : 148 - 160
[3] Risk factors for cerebral edema in children with diabetic ketoacidosis
Glaser, N
Barnett, P
McCaslin, I
Nelson, D
Trainor, J
Louie, J
Kaufman, F
Quayle, K
Roback, M
Malley, R
Kuppermann, N
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (04) : 264 - 269
[4] Glaser N., 2022, UpToDate
[5] ISPAD clinical practice consensus guidelines 2022: Diabetic ketoacidosis and hyperglycemic hyperosmolar state
Glaser, Nicole
Fritsch, Maria
Priyambada, Leena
Rewers, Arleta
Cherubini, Valentino
Estrada, Sylvia
Wolfsdorf, Joseph, I
Codner, Ethel
[J]. PEDIATRIC DIABETES, 2022, 23 (07) : 835 - 856
[6] Leukemoid Reaction in a Pediatric Patient With Diabetic Ketoacidosis
Gonzalez, Laura K.
Malhotra, Sonali
Levine, Marla
Jacobson-Dickman, Elka
[J]. PEDIATRIC EMERGENCY CARE, 2017, 33 (08) : E27 - E29
[7] The Medical Management of Cerebral Edema: Past, Present, and Future Therapies
Halstead, Michael R.
Geocadin, Romergryko G.
[J]. NEUROTHERAPEUTICS, 2019, 16 (04) : 1133 - 1148
[8] Leukemoid reaction in the pediatric population: etiologies, outcome, and implications
Hoofien, Assaf
Yarden-Bilavski, Havatzelet
Ashkenazi, Shai
Chodick, Gabriel
Livni, Gilat
[J]. EUROPEAN JOURNAL OF PEDIATRICS, 2018, 177 (07) : 1029 - 1036
[9] Hosseini SY., 2019, Patient Saf Qual Improve J, V7, P27, DOI [10.22038/psj.2019.35823.1195, DOI 10.22038/PSJ.2019.35823.1195]
[10] Hyperleukocytosis: Emergency Management
Jain, Richa
Bansal, Deepak
Marwaha, R. K.
[J]. INDIAN JOURNAL OF PEDIATRICS, 2013, 80 (02) : 144 - 148

← 1 2 →