Hypertensive Retinopathy is Not Associated with Low or High Birth Weight - Results from the Population-Based German Gutenberg Health Study

被引：2

作者：

Fiess, Achim ^{[1
]}

Gissler, Sandra ^{[1
]}

Wild, Philipp ^{[2
,3
,4
]}

Lackner, Karl ^{[5
]}

Muenzel, Thomas ^{[6
]}

Michal, Matthias ^{[7
]}

Urschitz, Michael ^{[8
]}

Pfeiffer, Norbert ^{[1
]}

Schuster, Alexander ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Ophthalmol, Langenbeck Str 1, D-55131 Mainz, Germany

[2] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Prevent Cardiol & Prevent Med, Ctr Cardiol, Mainz, Germany

[3] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Thrombosis & Hemostasis CTH, Mainz, Germany

[4] German Ctr Cardiovasc Res DZHK, Partner Site Rhine Main, Mainz, Germany

[5] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Clin Chem & Lab Med, Mainz, Germany

[6] Johannes Gutenberg Univ Mainz, Ctr Cardiol Cardiol 1, Univ Med Ctr, Mainz, Germany

[7] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Psychosomat Med & Psychotherapy, Mainz, Germany

[8] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Div Pediat Epidemiol, Inst Med Biostat Epidemiol & Informat, Mainz, Germany

来源：

CLINICAL OPHTHALMOLOGY | 2024年 / 18卷

关键词：

birth weight; hypertensive retinopathy; epidemiology; population-based study;

D O I：

10.2147/OPTH.S461261

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

This study investigates the association between self -reported birth weight (BW) and the prevalence of hypertensive retinopathy (HR) in a large population -based cohort in Germany, as part of the Gutenberg Health Study (GHS). The study involved analyzing fundus photographs of 6855 participants, aged 35 to 74, to assess signs of HR, classified according to the Mitchell -Wong Classification. The research aimed to explore the correlation between fetal growth restriction indicated by BW and the frequency of HR. The results showed that the frequency of HR did not significantly differ among groups with different BW ranges. In the univariable analysis, HR was initially associated with high BW, but this association disappeared after adjusting for age, sex, and cardiovascular risk factors. No association was found between low BW and HR. The study reveals novel insights as there are no prior population -based studies specifically exploring this association.

引用

页码：1797 / 1800

页数：4

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