An overview of systematic reviews of clinical studies of platelet-rich plasma for venous ulcers

被引：0

作者：

Shi, Tianbo ^{[1
,2
]}

Hu, Shouci ^{[3
]}

Hui, Jing ^{[4
]}

Ji, Yue ^{[5
]}

Zhang, Yalan ^{[6
]}

机构：

[1] Zhejiang Chinese Med Univ, Grad Sch, Hangzhou, Peoples R China

[2] Haining Canc Hosp, Haining Hosp TCM, Haining, Peoples R China

[3] Zhejiang Chinese Med Univ, Affiliated Hosp 1, Zhejiang Prov Hosp Chinese Med, Hangzhou, Peoples R China

[4] Sichuan Nursing Vocat Coll, Chengdu, Peoples R China

[5] Beijing Univ Tradit Chinese Med, Dongzhimen Hosp, Beijing, Peoples R China

[6] Fujian Med Univ, Affiliated Hosp 2, Dept Pharm, Quanzhou, Peoples R China

来源：

WOUND REPAIR AND REGENERATION | 2024年 / 32卷 / 05期

基金：

浙江省自然科学基金;

关键词：

evidence; platelet-rich plasma; treatment; venous ulcers; QUALITY;

D O I：

10.1111/wrr.13201

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

To evaluate the clinical evidence of platelet-rich plasma (PRP) in the treatment of venous ulcers (VUs). Electronic searches were conducted through the Cochrane Library, Web of Science, Embase and PubMed. AMSTAR-2 was used to assess the methodological quality. The quality of evidence was assessed using the GRADE system. According to AMSTAR-2, the methodological quality of the included reviews was generally inadequate owing to the limitations of entries 2, 4 and 7. Due to bias risk and imprecision, the evidence quality of the outcome measures was inadequate. In conclusion, PRP may have a therapeutic effect on VUs. However, this conclusion must be treated with caution due to methodological flaws of the included systematic reviews and meta-analyses.

引用

页码：655 / 660

页数：6

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