ANCA-Associated Vasculitis

被引：1

作者：

Sharma, Purva ^{[1
]}

Zonozi, Reza ^{[2
,3
]}

Geetha, Duvuru ^{[4
]}

机构：

[1] Northwell Hlth, Glomerular Ctr, Div Kidney Dis & Hypertens, Great Neck, NY USA

[2] Nephrol Associates Northern Virginia, Fairfax, VA USA

[3] Inova Fairfax Hosp, Falls Church, VA USA

[4] Johns Hopkins Univ, Sch Med, Div Nephrol, Baltimore, MD USA

来源：

ADVANCES IN KIDNEY DISEASE AND HEALTH | 2024年 / 31卷 / 03期

关键词：

ANCA; Rituximab; Plasmapheresis; Vasculitis; ANTIBODY-ASSOCIATED VASCULITIS; RHEUMATOLOGY CLASSIFICATION CRITERIA; 2022; AMERICAN-COLLEGE; ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES; DAILY ORAL CYCLOPHOSPHAMIDE; RANDOMIZED-TRIAL; PLASMA-EXCHANGE; RENAL SURVIVAL; CRESCENTIC GLOMERULONEPHRITIS; WEGENERS-GRANULOMATOSIS;

D O I：

10.1053/j.akdh.2024.04.005

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

ANCA-associated vasculitis (AAV) is a necrotizing, small-to-medium vessel vasculitis associated with significant morbidity and mortality. AAV is a systemic autoimmune disease affecting kidneys, eyes, sinuses, peripheral nerves, skin, and upper and lower respiratory tracts. AAV tends to present in characteristic phenotypes categorized clinically as granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic GPA (EGPA). Kidney involvement is a common feature of AAV, and has important implications on disease prognosis and management. Existing therapies have been refined and improvements in our understanding of the pathophysiology of AAV has led to approval of novel therapies. In this review, we provide an overview of epidemiology, disease mechanisms, clinical presentation and review therapeutic strategies for induction and maintenance of remission.

引用

页码：194 / 205

页数：12

共 97 条

[1]

Ahmad Youssef K, 2017, Hosp Pharm, V52, P294, DOI 10.1310/hpj5204-294

[2] Outcomes of remission induction therapy for ANCA-associated vasculitis in the elderly [J].

Aqeel, Faten ;

Xu, Lillian ;

Salas, Antonio ;

Wen, Yumeng ;

Eid, Shaker M. ;

Geetha, Duvuru .

CLINICAL RHEUMATOLOGY, 2023, 42 (09) :2427-2435

[3]

Asakawa Tomohiko, 2020, Case Rep Nephrol, V2020, P6343521, DOI 10.1155/2020/6343521

[4] Tubular Lesions Predict Renal Outcome in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis after Rituximab Therapy [J].

Berden, Annelies E. ;

Jones, Rachel B. ;

Erasmus, Dianhdra D. ;

Walsh, Michael ;

Noel, Laure-Helene ;

Ferrario, Franco ;

Waldherr, Ruediger ;

Bruijn, Jan A. ;

Jayne, David R. ;

Bajema, Ingeborg M. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2012, 23 (02) :313-321

[5] Induction and maintenance of remission with mycophenolate mofetil in ANCA-associated vasculitis: a systematic review and meta-analysis [J].

Berti, Alvise ;

Alsawas, Mouaz ;

Jawaid, Tabinda ;

Prokop, Larry J. ;

Lee, Jiwon M. ;

Jeong, Gwang Hun ;

Quintana, Luis F. ;

Moiseev, Sergey ;

Vaglio, August ;

Tesar, Vladimir ;

Geetha, Duvuru ;

Shin, Jae Il ;

Kronbichler, Andreas .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2022, 37 (11) :2190-2200

[6] D-penicillamine-induced ANCA-associated crescentic glomerulonephritis in Wilson disease [J].

Bienaime, Frank ;

Clerbaux, Gaetan ;

Plaisier, Emmanuelle ;

Mougenot, Beatrice ;

Ronco, Pierre ;

Rougier, Jean-Philippe .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2007, 50 (05) :821-825

[7]

Bir K, 2006, J RHEUMATOL, V33, P185

[8] DRB1*15 Allele Is a Risk Factor for PR3-ANCA Disease in African Americans [J].

Cao, Yali ;

Schmitz, John L. ;

Yang, Jiajin ;

Hogan, Susan L. ;

Bunch, Donna ;

Hu, Yichun ;

Jennette, Caroline E. ;

Berg, Elisabeth A. ;

Arnett, Frank C., Jr. ;

Jennette, J. Charles ;

Falk, Ronald J. ;

Preston, Gloria A. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 22 (06) :1161-1167

[9] Long-Term Rituximab Use to Maintain Remission of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis A Randomized Trial [J].

Charles, Pierre ;

Perrodeau, Elodie ;

Samson, Maxime ;

Bonnotte, Bernard ;

Neel, Antoine ;

Agard, Christian ;

Huart, Antoine ;

Karras, Alexandre ;

Lifermann, Francois ;

Godmer, Pascal ;

Cohen, Pascal ;

Hanrotel-Saliou, Catherine ;

Martin-Silva, Nicolas ;

Pugnet, Gregory ;

Maurier, Francois ;

Sibilia, Jean ;

Carron, Pierre-Louis ;

Gobert, Pierre ;

Meaux-Ruault, Nadine ;

Le Gallou, Thomas ;

Vinzio, Stephane ;

Viallard, Jean-Francois ;

Hachulla, Eric ;

Vinter, Christine ;

Puechal, Xavier ;

Terrier, Benjamin ;

Ravaud, Philippe ;

Mouthon, Luc ;

Guillevin, Loic .

ANNALS OF INTERNAL MEDICINE, 2020, 173 (03) :179-+

[10] Comparison of individually tailored versus fixed-schedule rituximab regimen to maintain ANCA-associated vasculitis remission: results of a multicentre, randomised controlled, phase III trial (MAINRITSAN2) [J].