Healthcare monitoring systems using mid-infrared and deep ultraviolet spectroscopy

被引:0
作者
Matsuura, Yuji [1 ]
机构
[1] Tohoku Univ, Grad Sch Biomed Engn, 6-6-05 Aoba, Sendai, Miyagi 9808579, Japan
来源
OPTICAL FIBERS AND SENSORS FOR MEDICAL DIAGNOSTICS, TREATMENT, AND ENVIRONMENTAL APPLICATIONS XXIV | 2024年 / 12835卷
关键词
Mid-infrared spectroscopy; blood glucose measurement; ultraviolet spectroscopy; breath analysis; ACETONE; FTIR;
D O I
10.1117/12.3009522
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Spectroscopy using mid-infrared light with a wavelength of 6 to 12 microns enables high-precision analysis of proteins, lipids, and carbohydrates that constitute living organisms. Recently, mid-infrared quantum cascade lasers and semiconductor detectors operating at room temperature have emerged in this field, increasing the feasibility of compact and inexpensive healthcare devices. In the deep ultraviolet region below 300 nm wavelength, various volatile gases show particularly strong absorption, and new applications are expected to emerge with the development of LEDs and new light sources. In this paper, non-invasive analysis of blood components based on mid-infrared photoacoustic spectroscopy is reported. As examples of applications of deep ultraviolet and vacuum ultraviolet spectroscopy using hollow optical fibers as microvolume and long optical path gas cells, the results of highly accurate measurement of acetone in exhaled breath, which is useful for metabolic measurements, is presented.
引用
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页数:8
相关论文
共 16 条
[1]   Measuring Breath Acetone for Monitoring Fat Loss: Review [J].
Anderson, Joseph C. .
OBESITY, 2015, 23 (12) :2327-2334
[2]   Noninvasive Body Fat Burn Monitoring from Exhaled Acetone with Si-doped WO3-sensing Nanoparticles [J].
Guentner, A. T. ;
Sievi, N. A. ;
Theodore, S. J. ;
Gulich, T. ;
Kohler, M. ;
Pratsinis, S. E. .
ANALYTICAL CHEMISTRY, 2017, 89 (19) :10578-10584
[3]   Real-Time Analysis of Isoprene in Breath by Using Ultraviolet-Absorption Spectroscopy with a Hollow Optical Fiber Gas Cell [J].
Iwata, Takuro ;
Katagiri, Takashi ;
Matsuura, Yuji .
SENSORS, 2016, 16 (12)
[4]   A review of breath analysis for diagnosis of human health [J].
Kim, K. -H. ;
Jahan, Shamin Ara ;
Kabir, Ehsanul .
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2012, 33 :1-8
[5]   New photoacoustic cell design for studying aqueous solutions and gels [J].
Kottmann, J. ;
Rey, J. M. ;
Sigrist, M. W. .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2011, 82 (08)
[6]   Glucose sensing in human epidermis using mid-infrared photoacoustic detection [J].
Kottmann, Jonas ;
Rey, Julien M. ;
Luginbuehl, Joachim ;
Reichmann, Ernst ;
Sigrist, Markus W. .
BIOMEDICAL OPTICS EXPRESS, 2012, 3 (04) :667-680
[7]   Vibrational Analysis of α-D-Glucose Trapped in Ar Matrix [J].
Kovacs, Attila ;
Ivanov, Alexander Yu. .
JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (07) :2151-2159
[8]   Vacuum Ultraviolet Absorption Spectroscopy Analysis of Breath Acetone Using a Hollow Optical Fiber Gas Cell [J].
Kudo, Yudai ;
Kino, Saiko ;
Matsuura, Yuji .
SENSORS, 2021, 21 (02) :1-11
[9]   Mid-infrared photoacoustic spectroscopy using a quantum cascade laser for non-invasive blood component analysis [J].
Maeno, Masanobu ;
Kino, Saiko ;
Matsuura, Yuji .
JAPANESE JOURNAL OF APPLIED PHYSICS, 2023, 62 (07)
[10]   AGE-RELATED CHANGES IN FTIR AND RAMAN SPECTRA OF HUMAN BLOOD [J].
Makhnii, T. ;
Ilchenko, O. ;
Reynt, A. ;
Pilgun, Y. ;
Kutsyk, A. ;
Krasnenkov, D. ;
Ivasyuk, M. ;
Kukharskyy, V. .
UKRAINIAN JOURNAL OF PHYSICS, 2016, 61 (10) :853-862