Vulvovaginal atrophy in women with and without a history of breast cancer: Baseline data from the PatiEnt satisfactiON studY (PEONY) in Italy

被引：7

作者：

Meriggiola, Maria Cristina ^{[1
]}

Villa, Paola ^{[2
]}

Maffei, Silvia ^{[3
,4
]}

Becorpi, Angelamaria ^{[5
]}

Di Paolantonio, Tiziana ^{[6
]}

Nicolucci, Antonio ^{[7
]}

Salvatore, Stefano ^{[8
]}

Nappi, Rossella E. ^{[9
,10
]}

机构：

[1] IRCCS Azienda Osped Univ Bologna, Gynecol & Physiopathol Human Reprod, I-40138 Bologna, Italy

[2] Catholic Univ, Policlin Univ A Gemelli IRCCS, Dept Obstet & Gynecol, I-00168 Rome, Italy

[3] Gabriele Monasterio Fdn, Gynaecol & Cardiovasc Endocrinol & Osteoporosis Un, Dept Cardiovasc Endocrinol & Metab, I-56124 Pisa, Italy

[4] Italian Natl Res Council CNR Pisa, I-56124 Pisa, Italy

[5] Careggi Univ Hosp, Dept Woman & Child Hlth, Sect Gynecol & Obstet, I-50134 Florence, Italy

[6] Shionogi Srl, I-00193 Rome, Italy

[7] Ctr Outcomes Res & Clin Epidemiol, CORESEARCH, I-65122 Pescara, Italy

[8] Univ Vita Salute San Raffaele, IRRCS San Raffaele Hosp, Obstet & Gynaecol Dept, I-20125 Milan, Italy

[9] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, I-27100 Pavia, Italy

[10] IRCCS S Matteo Fdn, Res Ctr Reprod Med & Gynecol Endocrinol, Menopause Unit, Piazzale Golgi 2, I-27100 Pavia, Italy

来源：

MATURITAS | 2024年 / 183卷

关键词：

Vulvovaginal atrophy; Local estrogens; Nonhormonal local treatments; Ospemifene; Breast cancer; QUALITY-OF-LIFE; GENITOURINARY SYNDROME; EXPERT OPINION; SEXUAL HEALTH; MENOPAUSE; SYMPTOMS; MANAGEMENT; OSPEMIFENE; SURVIVORS; IMPACT;

D O I：

10.1016/j.maturitas.2024.107950

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Objectives: To assess clinical characteristics of postmenopausal women with moderate/severe vulvovaginal atrophy, as well as its impact on sexual function, well-being, and quality of life, and to provide an overview of most used treatments. Study design: Ongoing longitudinal, observational study conducted in 17 Italian gynecology centers, involving women already treated or initiating a local vaginal estrogen therapy or ospemifene. We report baseline data for women with and without a history of breast cancer. Participants filled in self-reported questionnaires at study entry. Main outcome measures: Severity of vulvovaginal atrophy; ongoing treatments; patient-reported outcomes, including severity of symptoms, Day-to-Day Impact of Vaginal Aging (DIVA), Female Sexual Function Index (FSFI), Female Sexual Distress Scale-Revised (FSDS-R), and SF-12 (R) Health Survey.

引用

页数：9

共 43 条

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