Meningoencephalomyelitis Caused by Brucella canis : A Case Report and Literature Review

被引：2

作者：

Ishihara, Masaki ^{[1
,2
]}

Abe, Satoshi ^{[2
]}

Imaoka, Koichi ^{[3
]}

Nakagawa, Tomonori ^{[2
,4
]}

Kadota, Katsuhiko ^{[2
,5
]}

Oguro, Hiroaki ^{[2
,6
]}

Nakajima, Hideto ^{[1
]}

Yamaguchi, Shuhei ^{[2
,7
]}

Nagai, Atsushi ^{[2
]}

机构：

[1] Nihon Univ, Sch Med, Dept Med, Div Neurol, Tokyo, Japan

[2] Shimane Univ, Fac Med, Dept Neurol, Izumo, Japan

[3] Natl Inst Infect Dis, Dept Vet Sci, Tokyo, Japan

[4] Masuda Red Cross Hosp, Dept Neurol, Masuda, Japan

[5] Juntendo Univ, Grad Sch Med, Dept Emergency & Disaster Med, Tokyo, Japan

[6] Heisei Mem Hosp, Dept Neurol, Kashihara, Japan

[7] Shimane Prefectural Cent Hosp, Shimane Prefecture Bur, Izumo, Japan

来源：

INTERNAL MEDICINE | 2024年 / 63卷 / 12期

关键词：

neurobrucellosis; Brucella canis; meningoencephalomyelitis; fever of unknown origin; doxycycline; streptomycin; NEUROBRUCELLOSIS;

D O I：

10.2169/internalmedicine.2664-23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Human brucellosis, one of the most common zoonoses worldwide, is rare in Japan. Brucella canis is the specific pathogen of human brucellosis carried by dogs. According to an epidemiological study of B. canis infection in Japan, B. canis is the specific pathogen of human brucellosis in dogs. We herein report a rare case of meningoencephalomyelitis caused by B. canis in a 68-year-old Japanese man. Neurobrucellosis was diagnosed based on a serum tube agglutination test and abnormal cerebrospinal fluid findings. The patient was started on targeted treatment with a combination of doxycycline and streptomycin. Although extremely rare, neurobrucellosis should be considered in patients with a fever of unknown origin and unexplained neurological symptoms.

引用

页码：1823 / 1827

页数：5

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