Recent advances in the synthesis of phosphoramidate derivatives: A comprehensive review and analysis

被引：4

作者：

Dehmchi, Djenet Amel ^{[1
]}

Bouchareb, Fouzia ^{[1
,2
]}

Berredjem, Malika ^{[2
]}

机构：

[1] Chadli Bendjedid Univ, Fac Sci & Technol, Dept Chem, El Tarf, Algeria

[2] Badji Mokhtar Annaba Univ, Lab Appl Organ Chem LCOA, Synth Biomol & Mol Modelling Grp, Annaba, Algeria

来源：

SYNTHETIC COMMUNICATIONS | 2024年 / 54卷 / 22期

关键词：

Organophosphorus compounds; phosphoramidates; biological activity; applications; HEPATITIS-C VIRUS; FLAME-RETARDANT; INSECTICIDAL ACTIVITY; N-ACYLSULFONAMIDES; ORGANOPHOSPHORUS COMPOUNDS; ANTIBACTERIAL ACTIVITY; BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; INHIBITORS; ACID;

D O I：

10.1080/00397911.2024.2391917

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organophosphorus compounds (OPs) are a diverse group of chemical compounds that contain organic moieties directly bonded to phosphorus or through a heteroatom like oxygen, nitrogen, or sulfur. They are ubiquitous in the human environment due to their unique properties and high biological activity. OPs have been widely used in various fields such as agriculture (as pesticides), industry (for producing lubricants, hydraulic fluids, and plastics), medicine (as drugs against osteoporosis, anticancer, and antiviral compounds), and veterinary (as anthelmintics). As an important class of organophosphorus compounds, this review provides an overview of phosphoramidate compounds covering their synthetic pathways, a brief explanation of their mechanisms, and their various applications.

引用

页码：1909 / 1939

页数：31

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