Prevalence of functional gastrointestinal disorders in Saudi infants and toddlers: A cross-sectional multicenter study

被引：2

作者：

Hasosah, Mohammed ^{[1
,11
]}

Al Sarkhy, Ahmed ^{[2
]}

Alquiar, Khalid ^{[3
]}

Almuslami, Ibrahim ^{[4
]}

Alahmadi, Najat ^{[5
]}

Almehaidib, Ali ^{[6
]}

Alshahrani, Adel ^{[7
]}

Alanazi, Aziz ^{[8
]}

Khan, Muhammad ^{[1
]}

Aljohani, Abrar ^{[1
]}

Alanazi, Saqqar ^{[3
]}

Alhassan, Tariq ^{[2
]}

Alnaqeeb, Ahlam ^{[2
]}

Hameedaldeen, Marwah ^{[1
]}

Albalawi, Sanabil ^{[3
]}

Abdulmenem, Safa ^{[4
]}

Almehaidib, Ibrahim ^{[9
]}

Qurashi, Mansour ^{[10
]}

机构：

[1] King Saud Bin Abdulaziz Univ Hlth Sci, Pediat Gastroenterol Dept, Jeddah, Saudi Arabia

[2] King Saud Univ, King Saud Univ Med City, Pediat Gastroenterol Unit, Riyadh, Saudi Arabia

[3] King Salman Armed Forces Hosp, Pediat Gastroenterol, Tabuk, Saudi Arabia

[4] Maternal Children Hosp, Pediat Gastroenterol, Dammam, Saudi Arabia

[5] Maternal Children Hosp, Pediat Gastroenterol, Alahsa, Saudi Arabia

[6] King Faisal Specialist Hosp & Res Ctr, Pediat Gastroenterol, Riyadh, Saudi Arabia

[7] Maternal Children Hosp, Pediat Gastroenterol, Khamis Mushait, Saudi Arabia

[8] King Abdullah Int Med Res Ctr KAIMRC, Natl Guard Hosp, Pediat Gastroenterol, Riyadh, Saudi Arabia

[9] Imam Mohammed Ibn Saud Islamic Univ, Dept Internal Med, Riyadh, Saudi Arabia

[10] King Saud Bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr KAIMRC, Natl Guard Hosp, Neonatol Dept, Jeddah, Saudi Arabia

[11] King Saud bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr KAIMRC, Natl Guard Hosp, Coll Med,Pediat Gastroenterol Dept, Jeddah, Saudi Arabia

来源：

SAUDI JOURNAL OF GASTROENTEROLOGY | 2024年 / 30卷 / 03期

关键词：

Children; functional gastrointestinal disorders; risk factors; EPIDEMIOLOGY;

D O I：

10.4103/sjg.sjg_259_23

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: Functional gastrointestinal disorders (FGIDs) are common pediatric problems, but their prevalence in Saudi Arabia is unknown. We aimed to assess the prevalence of FGIDs and risk factors among children in six regions of Saudi Arabia. Methods: This was a cross-sectional multicenter study enrolling children aged 0-48 months, attending pediatric clinics. Questionnaires evaluated the clinical history, symptoms, and sociodemographic information. FGIDs were defined according to Rome IV criteria. Results: The study involved 1011 infants and toddlers (mean [standard deviation (SD)] aged, 21.7 [19.4] months; FGIDs and mean [SD] age 17.4 [16.4] months; controls). FGIDs were diagnosed in 483 (47.7%) of all infants and toddlers. The prevalence of FGIDs was significantly higher in children aged 0-12 months than in those aged 13-48 months (P < 0.001). The most common disorders were functional regurgitation (13.8%) in infants and functional constipation (9.6%) in toddlers. Univariate regression analysis confirmed that the rate of FGIDs was higher in term gestational age infants (odds ratio (OR) 2.7; 95% confidence interval (CI), 1.76-4.17, P < 0.001), in partial breastfeeding (OR 0.58; 95% CI, 0.40-0.84, P = 0.003), in formula feeding (OR 2.25; 95% CI, 1.51-3.35, P < 0.001), and in subjects with no history of food allergy (OR 2.40; 95% CI, 1.58-3.64, P < 0.001). Conclusions: FGIDs are common in Saudi infants and toddlers (47.7%). Regurgitation is most prevalent in infants, and functional constipation is most common in toddlers. Term gestational age infant, partial breastfeeding, formula feeding, and subjects with no history of food allergy are associated with the prevalence of FGIDs.

引用

页码：145 / 153

页数：9

共 29 条

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