Sulfur- and DABCO-Promoted Reaction between Alkylidene Rhodanines and Isothiocyanates: Access to Aminoalkylidene Rhodanines

被引：4

作者：

Farajpour, Behnaz ^{[1
]}

Alizadeh, Gul Bahar ^{[1
]}

Majedi, Soma ^{[2
]}

Moradkhani, Fatemeh ^{[3
]}

Majedi, Serveh ^{[4
]}

Notash, Behrouz ^{[5
]}

Hosseindoust, Benyamin ^{[1
]}

Shiri, Morteza ^{[1
]}

机构：

[1] Alzahra Univ, Fac Chem, Dept Organ Chem, Tehran 1993893973, Iran

[2] Tishk Int Univ, Appl Sci Fac, Med Anal Dept, Erbil 46001, Kurdistan Regio, Iraq

[3] Univ Tehran Med Sci, Fac Pharm, Pharmaceut Sci Res Ctr, Dept Med Chem, Tehran P94V 8MF, Iran

[4] Payame Noor Univ, Dept Chem, Tehran RG23 F4X, Iran

[5] Shahid Beheshti Univ, Dept Inorgan Chem, Tehran 1983969411, Iran

来源：

ACS OMEGA | 2024年 / 9卷 / 24期

基金：

美国国家科学基金会;

关键词：

DIASTEREOSELECTIVE SYNTHESIS; MICHAEL ADDITION; ONE-POT; CONDENSATION; DERIVATIVES; CONSTRUCTION; PYRAZOLONES; EFFICIENT; KETONES; DESIGN;

D O I：

10.1021/acsomega.4c03341

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this work, an efficient sulfur- and DABCO-promoted reaction for the synthesis of aminoalkylidene rhodanines from available alkylidene rhodanines and isothiocyanates is reported. A tandem process including sulfurative annulation/ring-opening by liberation of a CS2 molecule/olefination allows the synthesis of aminoalkylidene rhodanines with acceptable functional group tolerance. Chemo- and stereoselectivity, operational simplicity, and synthetically useful yields are some highlighted advantages of these transformations.

引用

页码：26607 / 26615

页数：9

共 3 条

[1] DABCO-promoted three-component reaction between amines, dialkyl acetylenedicarboxylates, and glyoxal
Ramesh, K.
Murthy, S. Narayana
Karnakar, K.
Nageswar, Y. V. D.
TETRAHEDRON LETTERS, 2011, 52 (30) : 3937 - 3941
[2] One-pot solvent-free three-component reaction between primary amines, carbon disulfide, and 5-alkylidene rhodanines: a convenient synthesis of asymmetric birhodanines
Nasiri, Farough
Nazari, Parisa
MOLECULAR DIVERSITY, 2018, 22 (03) : 601 - 608
[3] Sulfur/DABCO Promoted Reductive Coupling/Annulation Cascade Reaction between o -Hydroxy/Amino Nitrobenzenes and Benzaldehydes
Dang, Minh-Huy Dinh
Nguyen, Linh Ho Thuy
Tran, Phuong Hoang
SYNTHESIS-STUTTGART, 2020, 52 (11): : 1687 - 1694

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