Safety of fluoroquinolones

被引：3

作者：

Barberan, Jose ^{[1
]}

de la Cuerda, Alicia ^{[1
]}

Tejeda Gonzalez, Maria Isabel ^{[1
]}

Lopez Aparicio, Ana ^{[1
]}

Monfort Vinuesa, Carlos ^{[1
]}

Ramos Sanchez, Alejandro ^{[1
]}

Cristina Barberan, Lourdes ^{[1
]}

机构：

[1] Univ Camilo Jose Cela, Hosp Univ HM Monteprincipe, Fac HM Hosp Ciencias Salud, Madrid, Spain

来源：

REVISTA ESPANOLA DE QUIMIOTERAPIA | 2024年 / 37卷 / 02期

关键词：

Fluoroquinolones; adverse effects; neuropathy; tendon rupture; aortic aneurism; dysglycemia; ADVERSE DRUG-REACTIONS; CLOSTRIDIUM-DIFFICILE; ORAL FLUOROQUINOLONE; SEVERE DYSGLYCEMIA; AORTIC DISSECTION; DIABETIC-PATIENTS; RISK; HEPATOTOXICITY; ANEURYSMS; FOCUS;

D O I：

10.37201/req/143.2023

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Although they were initially well tolerated in randomized clinical trials, subsequent epidemiological studies have reported an increased risk of threatening, severe, long-lasting, disabling and irreversible adverse effects (AEs), related to neurotoxicity and collagen degradation, such as tendonitis, Achilles tendon rupture, aortic aneurysm, and retinal detachment. This article reviews the main potentially threatening AEs, the alarms issued by regulatory agencies and therapeutic alternatives.

引用

页码：127 / 133

页数：7

共 75 条

[1] Risk of hepatotoxicity associated with fluoroquinolones: A national case-control safety study [J].

Alshammari, Thamir M. ;

Larrat, E. Paul ;

Morrill, Haley J. ;

Caffrey, Aisling R. ;

Quilliam, Brian J. ;

LaPlante, Kerry L. .

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2014, 71 (01) :37-43

[2] How Safe are Fluoroquinolones for Diabetic Patients? A Systematic Review of Dysglycemic and Neuropathic Effects of Fluoroquinolones [J].

Althaqafi, Abdulrhman ;

Ali, Majid ;

Alzahrani, Yusuf ;

Ming, Long Chiau ;

Hussain, Zahid .

THERAPEUTICS AND CLINICAL RISK MANAGEMENT, 2021, 17 :1083-1090

[3] Fluoroquinolones and the risk of tendon injury: a systematic review and meta-analysis [J].

Alves, Carlos ;

Mendes, Diogo ;

Marques, Francisco Batel .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2019, 75 (10) :1431-1443

[4]

[Anonymous], 2023, Quantum Optimization Data Sheet

[5]

[Anonymous], 2019, EMA/430636/2019 Final Study Report V3.0

[6] Severe Dysglycemia with the Fluoroquinolones: A Class Effect? [J].

Aspinall, Sherrie L. ;

Good, Chester B. ;

Jiang, Rong ;

McCarren, Madeline ;

Dong, Diane ;

Cunningham, Francesca E. .

CLINICAL INFECTIOUS DISEASES, 2009, 49 (03) :402-408

[7] Signal Detection Between Fluoroquinolone Use and the Risk of Rhegmatogenous Retinal Detachment: Sequence Symmetry Analysis Using Nationwide South Korean Healthcare Database Between 2004 and 2015 [J].

Baek, Yeon-Hee ;

Park, Sang Jun ;

Jeong, Sohyun ;

Oh, In-Sun ;

Jeong, Han Eol ;

Park, Kyu Hyung ;

Shin, Ju-Young .

CLINICAL DRUG INVESTIGATION, 2018, 38 (12) :1179-1188

[8]

Ball P, 2000, J ANTIMICROB CHEMOTH, V46, P17

[9] Safety in the selection of oral antibiotic treatment in community infections, beyond COVID-19 [J].

Barberan, Jose ;

Cristina Barberan, Lourdes ;

de la Cuerda, Alicia .

REVISTA ESPANOLA DE QUIMIOTERAPIA, 2021, 34 (04) :289-297

[10] An evaluation of reports of ciprofloxacin, levofloxacin, and moxifloxacin-association neuropsychiatric toxicities, long-term disability, and aortic aneurysms/dissections disseminated by the Food and Drug Administration and the European Medicines Agency [J].

Bennett, Andrew C. ;

Bennett, Charles L. ;

Witherspoon, Bartlett J. ;

Knopf, Kevin B. .

EXPERT OPINION ON DRUG SAFETY, 2019, 18 (11) :1055-1063

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