Dupilumab treatment normalizes skin barrier function in children aged 6-11 years with moderate-to-severe atopic dermatitis

被引:0
|
作者
Cork, Michael J. [1 ]
Leung, Donald [2 ]
Ong, Peck [3 ]
Danby, Simon [1 ]
Ramirez-Gama, Marco [2 ]
Garcia, Shannon [2 ]
Patricia, Taylor [2 ]
Byers, Rob [1 ]
Matcher, Stephen [1 ]
Zahn, Joseph [4 ]
Bologna, Gabriel [5 ]
Zhang, Annie [6 ]
机构
[1] Univ Sheffield, Sheffield Dermatol Res, Sheffield, England
[2] Natl Jewish Hlth, Denver, CO USA
[3] Univ Southern Calif, Childrens Hosp Los Angeles, Los Angeles, CA USA
[4] Regeneron Pharmaceut Inc, Tarrytown, NY USA
[5] Ividata Life Sci, Levallois Perret, France
[6] Sanofi, Cambridge, MA USA
关键词
D O I
10.1093/bjd/ljae090.063
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
P036
引用
收藏
页码:I30 / I30
页数:1
相关论文
共 50 条
  • [41] DUPILUMAB TREATMENT IMPROVES HEALTH-RELATED QUALITY OF LIFE IN CHILDREN AGED 6 MONTHS TO 5 YEARS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS AND THEIR CAREGIVERS
    Paller, Amy S.
    Simpson, Eric L.
    Siegfried, Elaine C.
    Cork, Michael J.
    Wollenberg, Andreas
    Arkwright, Peter D.
    Zhang, Haixin
    Wang, Zhixiao
    Marco, Ainara Rodriguez
    ACTA DERMATO-VENEREOLOGICA, 2022, 102 : 49 - 49
  • [42] Dupilumab reduces biomarkers indicative of type 2 inflammation in children aged ≥ 6 months to 5 years with moderate-to-severe atopic dermatitis
    Paller, A.
    Guttman-Yassky, E.
    Boguniewicz, M.
    Levit, N.
    Wolfe, K.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2022, 142 (12) : S250 - S250
  • [43] Dupilumab treatment is not associated with an increased overall risk of infections in patients aged 6 months to 5 years with moderate-to-severe atopic dermatitis
    Siegfried, Elaine C.
    Cork, Michael J.
    Arkwright, Peter D.
    Wollenberg, Andreas
    Eichenfield, Lawrence F.
    Ramien, Michele
    Khokhar, Faisal A.
    Chen, Zhen
    Zhang, Annie
    Cyr, Sonya L.
    BRITISH JOURNAL OF DERMATOLOGY, 2023, 188
  • [44] Rapid response to dupilumab treatment in children with moderate-to-severe atopic dermatitis: A case series
    Votto, Martina
    Delle Cave, Francesco
    De Filippo, Maria
    Marseglia, Alessia
    Marseglia, Gian Luigi
    Brazzelli, Valeria
    Licari, Amelia
    PEDIATRIC ALLERGY AND IMMUNOLOGY, 2022, 33 : 31 - 33
  • [45] DUPILUMAB FOR TREATMENT OF SEVERE ATOPIC DERMATITIS IN CHILDREN UNDER 6 YEARS
    Bharathidasan, K.
    Diaz, A.
    Karkhanis, L.
    Diaz, J.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2020, 125 (05) : S116 - S117
  • [46] Dupilumab Treatment for 16 Weeks Reported Mild Increases in Eosinophil Levels Without Clinical Relevance in Children Aged 6-11 Years with Severe Atopic Dermatitis
    Paller, Amy S.
    Wollenberg, Andreas
    Cork, Michael
    Siegfried, Elaine
    Chen, Zhen
    Khokhar, Faisal
    Levit, Noah
    Marco, Ainara Rodriguez
    PEDIATRICS, 2022, 149 (01)
  • [47] Dupilumab is effective in children aged 6-11 years with severe atopic Dermatitis (AD) regardless of baseline serum total immunoglobulin E levels
    Cork, Michael J.
    Wollenberg, Andreas
    Siegfried, Elaine C.
    Arkwright, Peter D.
    Chen, Zhen
    Levit, Noah A.
    Marco, Ainara Rodriguez
    Radwan, Amr
    CLINICAL AND EXPERIMENTAL ALLERGY, 2021, 51 (12): : 1659 - 1659
  • [48] Dupilumab treatment significantly improves skin barrier function in adult and adolescent patients with moderate to severe atopic dermatitis
    Berdyshev, Evgeny
    Goleva, Elena
    Bissonnette, Robert
    Bronova, Irina
    Bronoff, Anna Sofia
    Richers, Brittany
    Garcia, Shannon
    Gama, Marco Ramirez
    Taylor, Patricia
    Bologna, Gabriel
    Agueusop, Inoncent
    Boguniewicz, Mark
    Harel, Sivan
    Levit, Noah
    Rossi, Ana
    Zhang, Annie
    Leung, Donald
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022, 149 (02) : AB10 - AB10
  • [49] Efficacy and safety of dupilumab for the treatment of moderate-to-severe atopic dermatitis in adults
    Zheng, Y.
    BRITISH JOURNAL OF DERMATOLOGY, 2019, 181 : 72 - 72
  • [50] Dupilumab treatment significantly improves skin barrier function in adult and adolescent patients with moderate to severe atopic dermatitis
    Iversen, L.
    Conrad, C.
    Karner, J.
    Costanzo, A.
    Cardner, M.
    Bier, K.
    Lohmann, F.
    Kolbinger, F.
    Jagiello, P.
    Ferrero, E.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2022, 142 (12) : S243 - S243