The Impact of Cardiovascular Antecedents on the Prognosis of COVID-19 Critically Ill Patients

被引:0
作者
Nechita, Luiza Camelia [1 ]
Ignat, Mariana Daniela [1 ]
Balta, Alexia Anastasia Stefania [1 ]
Barbu, Raisa Eloise [1 ]
Baroiu, Liliana [2 ,3 ]
Voinescu, Doina Carina [2 ,4 ]
Nechita, Aurel [2 ,5 ]
Debita, Mihaela [3 ,6 ]
Busila, Camelia [2 ,5 ]
Stefanopol, Ioana Anca [5 ,7 ]
机构
[1] Univ Galatzi, Doctoral Sch Biomed Sci, Galati 800008, Romania
[2] Univ Galatzi, Fac Med & Pharm, Clin Med Dept, Galati 800008, Romania
[3] Sf Cuv Parascheva Clin Hosp Infect Dis, Galati 800179, Romania
[4] Sf Apostol Andrei Clin Emergency Cty Hosp, Galati 800578, Romania
[5] Sf Ioan Clin Hosp Children, Galati 800487, Romania
[6] Univ Galatzi, Fac Med & Pharm, Med Dept, Galati 800008, Romania
[7] Univ Galatzi, Fac Med & Pharm, Clin Surg Dept, Galati 800008, Romania
关键词
cardiovascular disease; mechanical ventilation; COVID-19; COMPLICATIONS; PATHOGENESIS; SARS-COV-2; MECHANISMS; PNEUMONIA; SEQUELAE; INJURY; SPONGE;
D O I
10.3390/jcm13123518
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background/Objectives: The objective of the study is to analyze the impact of cardiovascular history on mortality in COVID-19 patients, hospitalized in the intensive care unit with indications for continuous positive airway pressure (CPAP) and subsequently mechanical ventilation, without oncological disease. Methods: A retrospective observational study was carried out on a group of 108 critical COVID-19 patients. We compared demographic data, paraclinical and clinical parameters, days of hospitalization, and mortality rate between two groups of patients, one group with a history of cardiovascular disease (81 patients) and a group without a history of cardiovascular disease (27 patients). Results: Patients with cardiovascular antecedents had a higher mortality rate than those without cardiovascular antecedents, presenting severe forms with shorter survival time in the intensive care unit and increased inflammatory evidence. Compared to patients without a history of cardiovascular illness, those with cardiovascular disease had a lower average age, and developed a severe form of COVID-19. Conclusions: Cardiovascular antecedents can worsen the prognosis of patients with COVID-19, requiring a careful screening and multidisciplinary approach.
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页数:13
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