Effectiveness of Early Multimodal Non-pharmacological Interventions in Cognitive Preservation in the Elderly

被引：2

作者：

Hsieh, Sun-Wung ^{[1
,2
,3
,4
]}

Hsiao, Shih-Fen ^{[5
,6
]}

Liaw, Lih-Jiun ^{[5
,6
]}

Huang, Ling-Chun ^{[2
,4
,7
]}

Yang, Yuan-Han ^{[2
,3
,4
,7
,8
,9
,10
]}

机构：

[1] Kaohsiung Med Univ, Kaohsiung Municipal Siaogang Hosp, Dept Neurol, Kaohsiung, Taiwan

[2] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Neurol, Kaohsiung, Taiwan

[3] Kaohsiung Med Univ, Coll Med, Fac Med, Dept Neurol, Kaohsiung, Taiwan

[4] Kaohsiung Med Univ, Neurosci Res Ctr, Kaohsiung, Taiwan

[5] Kaohsiung Med Univ, Coll Hlth Sci, Dept Phys Therapy, Kaohsiung, Taiwan

[6] Kaohsiung Med Univ Hosp, Dept Rehabil Med, Kaohsiung, Taiwan

[7] Kaohsiung Med Univ Hosp, Kaohsiung Municipal Ta Tung Hosp, Dept Neurol, Kaohsiung, Taiwan

[8] Kaohsiung Med Univ, Fac Med, Masters Program Neurol, Kaohsiung, Taiwan

[9] Chinese Mental Protect Assoc, Kaohsiung, Taiwan

[10] Kaohsiung Ta Tung Municipal Hosp, Dept Neurol, 68 Jhonghua 3rd Rd, Kaohsiung 80145, Taiwan

来源：

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS | 2024年 / 39卷

关键词：

dementia; cognitive preservation; multimodal non-pharmacological interventions; neuropsychiatric tests; cognitive assessment screening instrument; RANDOMIZED CONTROLLED-TRIAL; ALZHEIMERS-DISEASE; OLDER-PEOPLE; DEMENTIA; EXERCISE; THERAPY; EPIDEMIOLOGY; CALLIGRAPHY; IMPAIRMENT; COMPLAINTS;

D O I：

10.1177/15333175241256803

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

IntroductionMultimodal non-pharmacological interventions (MNPI) have been determined as effective in delaying cognitive deterioration. The effectiveness of timing of such interventions in elderly is less discussed. We compared the different effectiveness of MNPI in cognitive preservation in elderly subjects with and without dementia.MethodsWe enrolled volunteer the elderly subjects. Subjects were classified as dementia group and non-dementia group by instrument of ascertainment of dementia 8. All were assigned to attend 3 hours of MNPI (physical fitness training, Chinese capillary, and Chinese drawings and paintings) twice a week over a 16-week period. Neuropsychiatric tests, including Mini-Mental State Examination (MMSE), Cognitive Assessment Screening Instrument (CASI), clinical dementia rating (CDR), and neuropsychiatric inventory (NPI), were administered before and 1 year after MNPI. We demonstrated the changes of cognition and behavioral and psychological symptoms of dementia (BPSD) before and after MNPI. We compared the different effectiveness of cognition preservation between two groups.ResultsIn total, there were 43 participants in our study, including 18 with non-dementia and 25 with dementia. The non-dementia group had a significantly higher proportion of cognitive preservation in remote memory (100.0% vs 68.0%, P = .007), orientation (94.4% vs 48.0%, P = .001), drawing (94.4% vs 64.0%, P = .021) and language (77.8% vs 48.0%, P = .049) than the dementia group. The highest proportion of preserved cognition after MNPI was remote memory (100%), followed by orientation (94.4%) and drawing (94.4%) in the non-dementia group. The highest proportion of preserved cognition after MNPI was attention (72%) followed by remote memory (68%), recent memory (64%) and drawing (64%) in the dementia group. Overall, their improved rate in behavioral and psychological symptoms was 55.6%.ConclusionOur study concluded the benefits of early MNPI in cognition preservation in the elderly, especially in the field of remote memory, orientation, drawing and language.

引用

页数：11

共 51 条

[11] Exercise programs for people with dementia [J].