The Value of Metabolites and Vitamins for the Assessment of Nutritional Status in Hospitalized Patients

被引:1
作者
Verheul, Esmee A. H. [1 ]
Ouwerkerk, Joep J. J. [1 ]
Dijkink, Suzan [1 ]
Krijnen, Pieta [1 ]
Verhoeven, Aswin [2 ]
Giera, Martin [2 ]
Yeh, Daniel D. [3 ]
Schipper, Inger B. [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Trauma Surg, Post Zone K6-R,POB 9600, NL-2300 RC Leiden, Netherlands
[2] Leiden Univ, Ctr Prote & Metabol, Med Ctr, Leiden, Netherlands
[3] Univ Colorado Denver, Ernest E Moore Shock Trauma Ctr, Denver Hlth, Denver, CO USA
关键词
biomarkers; malnutrition; metabolites; nutritional status; vitamins; ASSESSMENT MNA; D DEFICIENCY; MALNUTRITION; DISEASE; PREVALENCE; IDENTIFICATION; HOMOCYSTEINE; ASSOCIATIONS; DEPLETION; CIRRHOSIS;
D O I
10.1097/TIN.0000000000000350
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Supplemental Digital Content is Available in the Text. This systematic review aims to summarize the currently available literature regarding the association of plasma metabolites and vitamins with the nutritional status in adult hospitalized patients. A systematic literature search was performed in PubMed and EMBASE, and all studies comparing metabolite or vitamin levels in malnourished versus well-nourished hospitalized patients were included. Twenty-three studies were eligible for inclusion, representing 3803 hospitalized patients. Several metabolites involved in the metabolism of methionine, purine, glutathione, carnitine, phenylalanine, and tryptophan, as well as some vitamins, seem to be associated with malnutrition in hospitalized patients. These compounds can potentially be used to assess nutritional status.
引用
收藏
页码:198 / 212
页数:15
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