Review of ionic liquid and ionogel-based biomaterials for advanced drug delivery

被引:9
作者
Kuddushi, Muzammil [1 ]
Xu, Ben Bin [2 ]
Malek, Naved [3 ]
Zhang, Xuehua [1 ]
机构
[1] Univ Alberta, Dept Chem & Mat Engn, Edmonton, AB T6G 1H9, Canada
[2] Northumbria Univ, Fac Engn & Environm, Mech & Construct Engn, Newcastle Upon Tyne NE1 8ST, Northumberland, England
[3] Sardar Vallabhbhai Natl Inst Technol, Ion Liquids Res Lab, Dept Chem, Surat 07, India
关键词
Ionic liquid; Ionogel; Stimuli responsive; Drug formulation; Drug delivery; POLY(IONIC LIQUID); TRANSDERMAL DELIVERY; ENERGY-STORAGE; SOL-GEL; PHARMACEUTICAL INGREDIENTS; SUPRAMOLECULAR HYDROGEL; POLYMER ELECTROLYTES; FACILE PREPARATION; HIGH-PERFORMANCE; AQUEOUS-SOLUTION;
D O I
10.1016/j.cis.2024.103244
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Ionic liquids (ILs) play a crucial role in the design of novel materials. The ionic nature of ILs provides numerous advantages in drug delivery, acting as a green solvent or active ingredient to enhance the solubility, permeability, and binding efficiency of drugs. They could also function as a structuring agent in the development of nano/micro particles for drug delivery, including micelles, vesicles, gels, emulsion, and more. This review summarize the ILs and IL-based gel structures with their advanced drug delivery applications. The first part of review focuses on the role of ILs in drug formulation and the applications of ILs in drug delivery. The second part of review offers a comprehensive overview of recent drug delivery applications of IL-based gel. It aims to offer new perspectives and attract more attention to open up new avenues in the biomedical applications of ILs and ILbased gels.
引用
收藏
页数:27
相关论文
共 272 条
[91]   Active pharmaceutical ingredients (APIs) in ionic liquids: An effective approach for API physiochemical parameter optimization [J].
Handa, Mayank ;
Almalki, Waleed H. ;
Shukla, Rahul ;
Afzal, Obaid ;
Altamimi, Abdulmalik Saleh Alfawaz ;
Beg, Sarwar ;
Rahman, Mahfoozur .
DRUG DISCOVERY TODAY, 2022, 27 (09) :2415-2424
[92]   Ultrastretchable, Adhesive, Fast Self-Healable, and Three-Dimensional Printable Photoluminescent Ionic Skin Based on Hybrid Network Ionogels [J].
Hao S. ;
Li T. ;
Yang X. ;
Song H. .
ACS Applied Materials and Interfaces, 2022, 14 (01) :2029-2037
[93]   A novel strategy for fabricating highly stretchable and highly conductive photoluminescent ionogels via an in situ self-catalytic cross-linking reaction in ionic liquids [J].
Hao, Shuai ;
Zhang, Jianxin ;
Yang, Xuemeng ;
Li, Tianci ;
Song, Hongzan .
JOURNAL OF MATERIALS CHEMISTRY C, 2021, 9 (17) :5789-5799
[94]   Challenges and strategies in anti-cancer nanomedicine development: An industry perspective [J].
Hare, Jennifer I. ;
Lammers, Twan ;
Ashford, Marianne B. ;
Puri, Sanyogitta ;
Storm, Gert ;
Barry, Simon T. .
ADVANCED DRUG DELIVERY REVIEWS, 2017, 108 :25-38
[95]   Self-Healing, Anti-Fatigue, antimicrobial ionic conductive hydrogels based on Choline-Amino acid polyionic liquids for Multi-Functional sensors [J].
He, Xiaoling ;
Dong, Jing ;
Zhang, Xiannan ;
Bai, Xinyuan ;
Zhang, Chen ;
Wei, Dongsheng .
CHEMICAL ENGINEERING JOURNAL, 2022, 435 (PT 2)
[96]   Thermoreversible ion gels with tunable melting temperatures from triblock and pentablock copolymers [J].
He, Yiyong ;
Lodge, Timothy P. .
MACROMOLECULES, 2008, 41 (01) :167-174
[97]   THE SOL-GEL PROCESS [J].
HENCH, LL ;
WEST, JK .
CHEMICAL REVIEWS, 1990, 90 (01) :33-72
[98]   High-performance, mechanically compliant silica-based ionogels for electrical energy storage applications [J].
Horowitz, Ariel I. ;
Panzer, Matthew J. .
JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (32) :16534-16539
[99]   The third evolution of ionic liquids:: active pharmaceutical ingredients [J].
Hough, Whitney L. ;
Smiglak, Marcin ;
Rodriguez, Hector ;
Swatloski, Richard P. ;
Spear, Scott K. ;
Daly, Daniel T. ;
Pernak, Juliusz ;
Grisel, Judith E. ;
Carliss, Richard D. ;
Soutullo, Morgan D. ;
Davis, James H., Jr. ;
Rogers, Robin D. .
NEW JOURNAL OF CHEMISTRY, 2007, 31 (08) :1429-1436
[100]   Ionic liquids revolutionizing biomedicine: recent advances and emerging opportunities [J].
Hu, Yanhui ;
Xing, Yuyuan ;
Yue, Hua ;
Chen, Tong ;
Diao, Yanyan ;
Wei, Wei ;
Zhang, Suojiang .
CHEMICAL SOCIETY REVIEWS, 2023, 52 (20) :7262-7293