Review of ionic liquid and ionogel-based biomaterials for advanced drug delivery

被引:9
作者
Kuddushi, Muzammil [1 ]
Xu, Ben Bin [2 ]
Malek, Naved [3 ]
Zhang, Xuehua [1 ]
机构
[1] Univ Alberta, Dept Chem & Mat Engn, Edmonton, AB T6G 1H9, Canada
[2] Northumbria Univ, Fac Engn & Environm, Mech & Construct Engn, Newcastle Upon Tyne NE1 8ST, Northumberland, England
[3] Sardar Vallabhbhai Natl Inst Technol, Ion Liquids Res Lab, Dept Chem, Surat 07, India
关键词
Ionic liquid; Ionogel; Stimuli responsive; Drug formulation; Drug delivery; POLY(IONIC LIQUID); TRANSDERMAL DELIVERY; ENERGY-STORAGE; SOL-GEL; PHARMACEUTICAL INGREDIENTS; SUPRAMOLECULAR HYDROGEL; POLYMER ELECTROLYTES; FACILE PREPARATION; HIGH-PERFORMANCE; AQUEOUS-SOLUTION;
D O I
10.1016/j.cis.2024.103244
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Ionic liquids (ILs) play a crucial role in the design of novel materials. The ionic nature of ILs provides numerous advantages in drug delivery, acting as a green solvent or active ingredient to enhance the solubility, permeability, and binding efficiency of drugs. They could also function as a structuring agent in the development of nano/micro particles for drug delivery, including micelles, vesicles, gels, emulsion, and more. This review summarize the ILs and IL-based gel structures with their advanced drug delivery applications. The first part of review focuses on the role of ILs in drug formulation and the applications of ILs in drug delivery. The second part of review offers a comprehensive overview of recent drug delivery applications of IL-based gel. It aims to offer new perspectives and attract more attention to open up new avenues in the biomedical applications of ILs and ILbased gels.
引用
收藏
页数:27
相关论文
共 272 条
[1]   Room temperature ionic liquids viscosity prediction from deep-learning models [J].
Acar, Zafer ;
Nguyen, Phu ;
Cui, Xiaoqi ;
Lau, Kah Chun .
ENERGY MATERIALS, 2023, 3 (05)
[2]   Ionic liquids as a potential tool for drug delivery systems [J].
Adawiyah, Noorul ;
Moniruzzaman, Muhammad ;
Hawatulailaa, Siti ;
Goto, Masahiro .
MEDCHEMCOMM, 2016, 7 (10) :1881-1897
[3]   Assessment of correlation between skin target site free drug concentration and the in vivo topical antiviral efficacy in hairless mice for (E)-5-(2-bromovinyl)-2′-deoxyuridine and acyclovir formulations [J].
Afouna, MI ;
Mehta, SC ;
Ghanem, AH ;
Higuchi, WI ;
Kern, ER ;
De Clercq, E ;
El-Shattawy, HH .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1998, 87 (08) :917-921
[4]   Ionic liquids for addressing unmet needs in healthcare [J].
Agatemor, Christian ;
Ibsen, Kelly N. ;
Tanner, Eden E. L. ;
Mitragotri, Samir .
BIOENGINEERING & TRANSLATIONAL MEDICINE, 2018, 3 (01) :7-25
[5]   Extremely Soft, Conductive, and Transparent Ionic Gels by 3D Optical Printing [J].
Ahmed, Kumkum ;
Naga, Naofumi ;
Kawakami, Masaru ;
Furukawa, Hidemitsu .
MACROMOLECULAR CHEMISTRY AND PHYSICS, 2018, 219 (24)
[6]   Fluidic flow delay by ionogel passive pumps in microfluidic paper-based analytical devices [J].
Akyazi, Tugce ;
Saez, Janire ;
Elizalde, Jorge ;
Benito-Lopez, Fernando .
SENSORS AND ACTUATORS B-CHEMICAL, 2016, 233 :402-408
[7]   Simultaneous determination of doxorubicin and dasatinib as two breast anticancer drugs uses an amplified sensor with ionic liquid and ZnO nanoparticle [J].
Alavi-Tabari, Seyed A. R. ;
Khalilzadeh, Mohammad A. ;
Karimi-Maleh, Hassan .
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2018, 811 :84-88
[8]   Solubility enhancement of glibenclamide in choline-tryptophan ionic liquid: Preparation, characterization and mechanism of solubilization [J].
Alawi, Mahmoud A. ;
Harridan, Imad I. ;
Sallam, ALSayed A. ;
Abu Heshmeh, Najiah .
JOURNAL OF MOLECULAR LIQUIDS, 2015, 212 :629-634
[9]   Biocompatible Ionic Liquid-Mediated Micelles for Enhanced Transdermal Delivery of Paclitaxel [J].
Ali, Md Korban ;
Moshikur, Rahman Md ;
Wakabayashi, Rie ;
Moniruzzaman, Muhammad ;
Goto, Masahiro .
ACS APPLIED MATERIALS & INTERFACES, 2021, 13 (17) :19745-19755
[10]   Biocompatible Ionic Liquid Surfactant-Based Microemulsion as a Potential Carrier for Sparingly Soluble Drugs [J].
Ali, Md Korban ;
Moshikur, Rahman Md ;
Wakabayashi, Rie ;
Moniruzzaman, Muhammad ;
Kamiya, Noriho ;
Goto, Masahiro .
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2020, 8 (16) :6263-6272