Impact of Scattering Foil Composition on Electron Energy Distribution in a Clinical Linear Accelerator Modified for FLASH Radiotherapy: A Monte Carlo Study

被引:1
作者
Chow, James C. L. [1 ,2 ]
Ruda, Harry E. [3 ,4 ]
机构
[1] Univ Hlth Network, Princess Margaret Canc Ctr, Radiat Med Program, Toronto, ON M5G 1X6, Canada
[2] Univ Toronto, Dept Radiat Oncol, Toronto, ON M5T 1P5, Canada
[3] Univ Toronto, Fac Appl Sci & Engn, Ctr Adv Nanotechnol, Toronto, ON M5S 3E4, Canada
[4] Univ Toronto, Dept Mat Sci & Engn, Toronto, ON M5S 3E4, Canada
关键词
FLASH radiotherapy; FLASH effect; scattering foil; electron beam; Monte Carlo simulation; electron energy distribution; linear accelerator; LATERAL BUILDUP RATIO; BEAMS;
D O I
10.3390/ma17133355
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
This study investigates how scattering foil materials and sampling holder placement affect electron energy distribution in electron beams from a modified medical linear accelerator for FLASH radiotherapy. We analyze electron energy spectra at various positions-ionization chamber, mirror, and jaw-to evaluate the impact of Cu, Pb-Cu, Pb, and Ta foils. Our findings show that close proximity to the source intensifies the dependence of electron energy distribution on foil material, enabling precise beam control through material selection. Monte Carlo simulations are effective for designing foils to achieve desired energy distributions. Moving the sampling holder farther from the source reduces foil material influence, promoting more uniform energy spreads, particularly in the 0.5-10 MeV range for 12 MeV electron beams. These insights emphasize the critical role of tailored material selection and sampling holder positioning in optimizing electron energy distribution and fluence intensity for FLASH radiotherapy research, benefiting both experimental design and clinical applications.
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页数:12
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