Tissue Engineering and Ophthalmology

被引:2
作者
Utine, Canan Asli [1 ,2 ]
Guven, Sinan [2 ,3 ,4 ]
机构
[1] Dokuz Eylul Univ, Dept Ophthalmol, Fac Med, Izmir, Turkiye
[2] Izmir Biomed & Genome Ctr, Izmir, Turkiye
[3] Dokuz Eylul Univ, Izmir Int Biomed & Genome Inst, Izmir, Turkiye
[4] Dokuz Eylul Univ, Fac Med, Dept Med Biol & Genet, Izmir, Turkiye
来源
TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY | 2024年 / 54卷 / 03期
关键词
Tissue engineering; gene therapy; disease model; drug development; regenerative medicine; PLURIPOTENT STEM-CELLS; VORETIGENE NEPARVOVEC; RETINAL REPAIR; TRANSPLANTATION; DELIVERY; THERAPY; RELEASE; EYE; DIFFERENTIATE; REGENERATION;
D O I
10.4274/tjo.galenos.2024.49779
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Tissue engineering (TE) is a field of science that combines biological, engineering, and medical sciences and allows the development of disease models, drug development and gene therapy studies, and even cellular or tissue -based treatments developed by engineering methods. The eye is an organ that is easily accessible and amenable to engineering applications, paving the way for TE in ophthalmology. TE studies are being conducted on a wide range of topics, including the tear film, eyelids, cornea, optic nerve, glaucoma, and retinal diseases. With the rapid scientific advances in the field, it seems that TE is radically modifying the management of ocular disorders.
引用
收藏
页码:159 / 169
页数:11
相关论文
共 134 条
[1]   Multi-corneal barrier-on-a-chip to recapitulate eye blinking shear stress forces [J].
Abdalkader, Rodi ;
Kamei, Ken-ichiro .
LAB ON A CHIP, 2020, 20 (08) :1410-1417
[2]   Designing Scaffolds for Corneal Regeneration [J].
Ahearne, Mark ;
Fernandez-Perez, Julia ;
Masterton, Sophia ;
Madden, Peter W. ;
Bhattacharjee, Promita .
ADVANCED FUNCTIONAL MATERIALS, 2020, 30 (44)
[3]   Hydrocortisone nanosuspensions for ophthalmic delivery: A comparative study between microfluidic nanoprecipitation and wet milling [J].
Ali, Hany S. M. ;
York, Peter ;
Ali, Ahmed M. A. ;
Blagden, Nicholas .
JOURNAL OF CONTROLLED RELEASE, 2011, 149 (02) :175-181
[4]   Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration [J].
Ambati, Meenakshi ;
Apicella, Ivana ;
Wang, Shao-bin ;
Narendran, Siddharth ;
Leung, Hannah ;
Pereira, Felipe ;
Nagasaka, Yosuke ;
Huang, Peirong ;
Varshney, Akhil ;
Baker, Kirstie L. ;
Marion, Kenneth M. ;
Shadmehr, Mehrdad ;
Stains, Cliff, I ;
Werner, Brian C. ;
Sadda, Srinivas R. ;
Taylor, Ethan W. ;
Sutton, S. Scott ;
Magagnoli, Joseph ;
Gelfand, Bradley D. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (41)
[5]   Plasma Rich in Growth Factors for the Treatment of Ocular Surface Diseases [J].
Anitua, Eduardo ;
Muruzabal, Francisco ;
de la Fuente, Maria ;
Merayo, Jesus ;
Duran, Juan ;
Orive, Gorka .
CURRENT EYE RESEARCH, 2016, 41 (07) :875-882
[6]   Embryonic stem cells that differentiate into RPE cell precursors in vitro develop into RPE cell monolayers in vivo [J].
Aoki, H ;
Hara, A ;
Nakagawa, S ;
Motohashi, T ;
Hirano, M ;
Takahashi, Y ;
Kunisada, T .
EXPERIMENTAL EYE RESEARCH, 2006, 82 (02) :265-274
[7]   Development of lacrimal gland organoids from iPSC derived multizonal ocular cells [J].
Asal, Melis ;
Kocak, Gamze ;
Sari, Vedat ;
Recber, Tuba ;
Nemutlu, Emirhan ;
Utine, Canan Asli ;
Guven, Sinan .
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2023, 10
[8]   The first-in-human implantation of the CorNeat keratoprosthesis [J].
Bahar, Irit ;
Reitblat, Olga ;
Livny, Eitan ;
Litvin, Gilad .
EYE, 2023, 37 (07) :1331-1335
[9]   A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells [J].
Bai, Jing ;
Fu, Haojie ;
Bazinet, Lauren ;
Birsner, Amy E. ;
D'Amato, Robert J. .
FRONTIERS IN PHARMACOLOGY, 2020, 11
[10]   Decellularized optic nerve functional scaffold transplant facilitates directional axon regeneration and remyelination in the injured white matter of the rat spinal cord [J].
Bai, Yu-Rong ;
Lai, Bi-Qin ;
Han, Wei-Tao ;
Sun, Jia-Hui ;
Li, Ge ;
Ding, Ying ;
Zeng, Xiang ;
Ma, Yuan-Huan ;
Zeng, Yuan-Shan .
NEURAL REGENERATION RESEARCH, 2021, 16 (11) :2276-2283