Sex differences in the plasma glucagon responses to a high carbohydrate meal and a glucose drink in type 2 diabetes

被引：3
作者：
Huang, Weikun [1 ]
Xie, Cong [1 ,2 ]
Jones, Karen L. [1 ,2 ]
Horowitz, Michael [1 ,2 ]
Rayner, Christopher K. [1 ,3 ]
Wu, Tongzhi [1 ]
机构：
[1] Univ Adelaide, Ctr Res Excellence Translating Nutr Sci Good Hlth, Adelaide Med Sch, Adelaide, Australia
[2] Royal Adelaide Hosp, Endocrine & Metab Unit, Adelaide, Australia
[3] Royal Adelaide Hosp, Dept Gastroenterol & Hepatol, Adelaide, Australia
来源：
DIABETES RESEARCH AND CLINICAL PRACTICE | 2024年 / 214卷
基金：
英国医学研究理事会;
关键词：
Sex disparity; Glucagon; Hyperglucagonaemia; Glycaemic control; Type; 2; diabetes;
D O I：
10.1016/j.diabres.2024.111769
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Elevated fasting glucagon concentrations and/or attenuated postprandial glucagon suppression are characteristics of type 2 diabetes (T2D) and contribute to hyperglycaemia. This study shows that hyperglucagonaemia is more prominent in males than females after a nutrient load in T2D, adding insights into sex differences in relation to the pathophysiology of T2D.
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页数：3
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