Matching Patients to Accelerate Clinical Trials (MPACT): Enabling Technology for Oncology Clinical Trial Workflow

被引：0

作者：

Do, Nhan V. ^{[1
,3
]}

Elbers, Danne C. ^{[1
,2
]}

Fillmore, Nathanael R. ^{[1
,2
]}

Ajjarapu, Samuel ^{[1
]}

Bergstrom, Steven J. ^{[1
]}

Bihn, John ^{[1
]}

Corrigan, June K. ^{[1
]}

Dhond, Rupali ^{[1
,3
]}

Dipietro, Svitlana ^{[1
]}

Dolgin, Arkadiy ^{[1
]}

Feldman, Theodore C. ^{[1
]}

Goryachev, Sergey D. ^{[1
]}

Huhmann, Linden B. ^{[1
]}

La, Jennifer ^{[1
]}

Marcantonio, Paul A. ^{[1
]}

McGrath, Kyle M. ^{[1
]}

Miller, Stephen J. ^{[1
]}

Nguyen, Vinh Q. ^{[1
]}

Schneeloch, George R. ^{[1
]}

Sung, Feng-Chi ^{[1
]}

Swinnerton, Kaitlin N. ^{[1
]}

Tarren, Amelia H. ^{[1
]}

Tosi, Hannah M. ^{[1
]}

Valley, Danielle ^{[1
]}

Vo, Austin D. ^{[1
]}

Yildirim, Cenk ^{[1
]}

Zheng, Chunlei ^{[1
]}

Zwolinski, Robert ^{[1
]}

Sarosy, Gisele A. ^{[4
]}

Loose, David ^{[4
]}

Shannon, Colleen ^{[1
]}

Brophy, Mary T. ^{[1
,3
]}

机构：

[1] VA Boston Healthcare Syst, Boston, MA 02115 USA

[2] Harvard Med Sch, Boston, MA USA

[3] Boston Univ, Sch Med, Boston, MA 02118 USA

[4] NCI, Bethesda, MD USA

来源：

MEDINFO 2023 - THE FUTURE IS ACCESSIBLE | 2024年 / 310卷

关键词：

Clinical trials; workflow; NLP;

D O I：

10.3233/SHTI231132

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

Clinical trial enrollment is impeded by the significant time burden placed on research coordinators screening eligible patients. With 50,000 new cancer cases every year, the Veterans Health Administration (VHA) has made increased access for Veterans to high-quality clinical trials a priority. To aid in this effort, we worked with research coordinators to build the MPACT (Matching Patients to Accelerate Clinical Trials) platform with a goal of improving efficiency in the screening process. MPACT supports both a trial prescreening workflow and a screening workflow, employing Natural Language Processing and Data Science methods to produce reliable phenotypes of trial eligibility criteria. MPACT also has a functionality to track a patient's eligibility status over time. Qualitative feedback has been promising with users reporting a reduction in time spent on identifying eligible patients.

引用

页码：1086 / 1090

页数：5

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