Lung Cancer Adoptive Cell Therapy: Inspiring TIL ACT Comes Center Stage

被引：3

作者：

Lotze, Michael T. ^{[1
]}

Maeurer, Markus ^{[2
]}

Quezada, Sergio A. ^{[3
]}

Coukos, George ^{[4
]}

机构：

[1] Univ Pittsburgh Med Ctr, Hillman Canc Ctr, 5115 Ctr Ave, Pittsburgh, PA 15232 USA

[2] Champalimaud Fdn, Lisbon, Portugal

[3] UCL, Canc Inst, London, England

[4] Univ Lausanne, Ludwig Inst, Lausanne, Switzerland

来源：

CANCER DISCOVERY | 2024年 / 14卷 / 08期

关键词：

D O I：

10.1158/2159-8290.CD-24-0645

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Schoenfeld and colleagues report, in this issue, a measurable objective response rate in 6/28 (21.4%) of patients with advanced non-small cell lung cancer treated with lifileucel, a cell therapy product based on autologous tumor-infiltrating lymphocytes (TIL). Extending solid evidence in advanced melanoma that led to FDA approval of lifileucel, this new evidence bodes well for treating patients with other common tumor histologies, justifying important efforts by a large number of academic and biotechnology companies engaged in improving the TIL process. See related article by Schoenfeld et al., p. 1389 (1).

引用

页码：1366 / 1368

页数：3

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