Mechanistic insights of phospholipid modulation in a pentameric ligand-gated ion channel

被引:0
|
作者
Tan, Brandon [1 ]
Xu, Hanrui [1 ]
Cheng, Wayland W. [1 ]
机构
[1] Washington Univ, Dept Anesthesiol, Sch Med, St Louis, MO USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
2197-Pos
引用
收藏
页码:394A / 394A
页数:1
相关论文
共 50 条
  • [1] Structural basis for alcohol modulation of a pentameric ligand-gated ion channel
    Howard, Rebecca J.
    Murail, Samuel
    Ondricek, Kathryn E.
    Corringer, Pierre-Jean
    Lindahl, Erik
    Trudell, James R.
    Harris, R. Adron
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (29) : 12149 - 12154
  • [2] Structural mechanism of lipid modulation of a pentameric ligand-gated ion channel
    Cheng, Wayland W.
    Petroff, John T.
    Dietzen, Noah
    ANESTHESIA AND ANALGESIA, 2021, 132 (5S_SUPPL): : 85 - 86
  • [3] Allosteric Modulation of the Pentameric Ligand-Gated Ion Channel ELIC by Barbiturates
    De Peuter, Hannelore
    Brams, Marijke
    Joseph, Delphine
    Bertrand, Daniel
    Ulens, Chris
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 300A - 300A
  • [4] Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel
    Karlsson, Emelia
    Anden, Olivia
    Fan, Chen
    Fourati, Zaineb
    Haouz, Ahmed
    Zhuang, Yuxuan
    Howard, Rebecca J.
    Delarue, Marc
    Lindahl, Erik
    BRITISH JOURNAL OF PHARMACOLOGY, 2025,
  • [5] Structural basis for the modulation of pentameric ligand-gated ion channel function by lipids
    Thompson, Mackenzie J.
    Baenziger, John E.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2020, 1862 (09):
  • [6] Allosteric Modulation via Transmembrane Interfaces in a Pentameric Ligand-Gated Ion Channel
    Howard, Rebecca J.
    Zhuang, Yuxuan
    Nakamura, Shinjiro
    Lycksell, Marie
    Kiik, Helen
    Rovsnik, Urska
    Bergh, Cathrine
    Heusser, Stephanie A.
    Orellana, Laura
    Lindahl, Erik
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 245A - 246A
  • [7] A pentameric, ligand-gated ion channel from a bacterium
    Braun, Andrew
    CHANNELS, 2008, 2 (03) : 155 - 155
  • [8] Elephants in the Dark: Insights and Incongruities in Pentameric Ligand-gated Ion Channel Models
    Howard, Rebecca J.
    JOURNAL OF MOLECULAR BIOLOGY, 2021, 433 (17)
  • [9] Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation
    Petroff, John T.
    Dietzen, Noah M.
    Santiago-McRae, Ezry
    Deng, Brett
    Washington, Maya S.
    Chen, Lawrence J.
    Moreland, K. Trent
    Deng, Zengqin
    Rau, Michael
    Fitzpatrick, James A. J.
    Yuan, Peng
    Joseph, Thomas T.
    Henin, Jerome
    Brannigan, Grace
    Cheng, Wayland W. L.
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [10] Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation
    John T. Petroff
    Noah M. Dietzen
    Ezry Santiago-McRae
    Brett Deng
    Maya S. Washington
    Lawrence J. Chen
    K. Trent Moreland
    Zengqin Deng
    Michael Rau
    James A. J. Fitzpatrick
    Peng Yuan
    Thomas T. Joseph
    Jérôme Hénin
    Grace Brannigan
    Wayland W. L. Cheng
    Nature Communications, 13