The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes

被引：12
作者：
Liang, Jing [1 ,2 ]
He, Yiwen [1 ,3 ]
Huang, Chunxia [4 ]
Ji, Fengjie [5 ]
Zhou, Xihong [1 ,2 ]
Yin, Yulong [1 ,2 ]
机构：
[1] Inst Subtrop Agr, Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg, Changsha 410125, Peoples R China
[2] Univ Chinese Acad Sci, Coll Adv Agr Sci, Beijing 100049, Peoples R China
[3] Hunan Normal Univ, Coll Life Sci, Hunan Prov Key Lab Anim Intestinal Funct & Regulat, Hunan Int Joint Lab Anim Intestinal Ecol & Hlth, Changsha 410081, Peoples R China
[4] Changsha Med Univ, Sch Stomatol, Changsha 410219, Peoples R China
[5] Trop Crops Genet Resources Inst, Chinese Acad Trop Agr Sci, Haikou 571101, Peoples R China
来源：
CURRENT PHARMACEUTICAL DESIGN | 2024年 / 30卷 / 20期
关键词：
Glucose metabolism; lipid metabolism; selenium; selenoproteins; diabetes; OXIDATIVE STRESS; THYROID-HORMONE; SELENIUM; METABOLISM; SUPPLEMENTATION; GLUTATHIONE;
D O I：
10.2174/0113816128302667240422110226
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Selenium is an essential micronutrient required for the synthesis and function of selenoproteins, most of which are enzymes involved in maintaining oxidative balance in the body. Diabetes is a group of metabolic disorders characterized by high blood glucose levels over a prolonged period of time. There are three main types of diabetes: type 1, type 2, and gestational diabetes. This review summarizes recent advances in the field of diabetes research with an emphasis on the roles of selenoproteins on metabolic disturbance in diabetes. We also discuss the interaction between selenoproteins and glucose and lipid metabolism to provide new insights into the prevention and treatment of diabetes.
引用
收藏
页码：1541 / 1547
页数：7
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