The Current and Future Roles of Precision Oncology in Advanced Breast Cancer

被引：1

作者：

Jacene, Heather ^{[1
]}

Dietsche, Eric ^{[2
]}

Specht, Jennifer ^{[3
]}

机构：

[1] Dana Farber Brigham Canc Ctr, Imaging Radiol, Boston, MA 01757 USA

[2] Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Dept Radiol, Providence, RI USA

[3] Univ Washington, Fred Hutch Canc Ctr, Dept Med, Div Hematol & Oncol & Clin Res, Seattle, WA USA

来源：

JOURNAL OF NUCLEAR MEDICINE | 2024年 / 65卷 / 03期

关键词：

breast cancer; molecular imaging; precision; FDG; FES; PET; INVASIVE LOBULAR CARCINOMA; NEOADJUVANT CHEMOTHERAPY; F-18-FDG PET/CT; PROGESTERONE-RECEPTOR; PATHOLOGICAL RESPONSE; DOUBLE-BLIND; FDG-PET/CT; OPEN-LABEL; PHASE-II; TRASTUZUMAB;

D O I：

10.2967/jnumed.122.264882

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Breast cancer is a common but heterogeneous disease characterized by several biologic features, including tumor grade, hormone receptor status, human epidermal growth factor receptor 2 status, and gene expression assays. These biologic and genomic features drive treatment decisions. In the advanced disease setting, inter- and intrapatient tumor heterogeneity is increasingly recognized as a challenge for optimizing treatment. Recent evidence and the recent approval of novel radiopharmaceuticals have increased recognition and acceptance of the potential of molecular imaging as a biomarker to impact and guide management decisions for advanced breast cancer.

引用

页码：349 / 356

页数：8

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