Community collaboration to advance racial/ethnic equity in colorectal Cancer screening: Protocol for a multilevel intervention to improve screening and follow-up in community Health centers

被引：0

作者：

May, Folasade P. ^{[1
,2
,3
,4
]}

Brodney, Suzanne ^{[5
]}

Tuan, Jessica J. ^{[4
]}

Syngal, Sapna ^{[6
,7
,8
]}

Chan, Andrew T. ^{[8
,9
,10
,11
,12
,13
]}

Glenn, Beth ^{[4
,14
,15
]}

Johnson, Gina ^{[16
]}

Chang, Yuchiao ^{[5
,8
]}

Drew, David A. ^{[8
,9
,10
]}

Moy, Beverly ^{[17
]}

Rodriguez, Nicolette J. ^{[6
,8
]}

Warner, Erica T. ^{[5
,8
,9
,18
]}

Anyane-Yeboa, Adjoa ^{[8
,9
,10
]}

Ukaegbu, Chinedu ^{[7
,8
]}

Davis, Anjelica Q. ^{[19
]}

Schoolcraft, Kimberly ^{[19
]}

Regan, Susan ^{[5
]}

Yoguez, Nathan ^{[8
,9
,10
]}

Kuney, Samantha ^{[7
]}

Le Beaux, Kelley ^{[16
]}

Jeffries, Catherine ^{[16
]}

Lee, Ellen T. ^{[5
]}

Bhat, Roopa ^{[5
]}

Haas, Jennifer S. ^{[5
,19
]}

机构：

[1] Univ Calif Los Angeles, Dept Med, David Geffen Sch Med, UCLA Ronald Reagan Med Ctr, 757 Westwood Plaza, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Vatche & Tamar Manoukian Div Digest Dis,Ctr Hlth S, 650 S Charles E Young Dr,Suite A2 125, Los Angeles, CA 90095 USA

[3] Greater Los Angeles Vet Affairs Healthcare Syst, Los Angeles, CA USA

[4] Jonsson Comprehens Canc Ctr, UCLA Kaiser Permanente Ctr Hlth Equ, Ctr Hlth Sci, 650 S Charles E Young Dr,Suite A2-125, Los Angeles, CA 90095 USA

[5] Massachusetts Gen Hosp, Div Gen Internal Med, Boston, MA USA

[6] Brigham & Womens Hosp, Div Gastroenterol, Boston, MA USA

[7] Dana Farber Canc Inst, Populat Sci & Canc Genet & Prevent Div, Boston, MA USA

[8] Harvard Med Sch, Boston, MA USA

[9] Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA USA

[10] Massachusetts Gen Hosp, Div Gastroenterol, Boston, MA USA

[11] Broad Inst MIT & Harvard, Cambridge, MA USA

[12] Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA USA

[13] Harvard TH Chan Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA USA

[14] Univ Calif Los Angeles, Fielding Sch Publ Hlth, Dept Hlth Policy & Management, Los Angeles, CA USA

[15] Univ Calif Los Angeles, UCLA Ctr Canc Prevent & Control Res, UCLA Jonsson Comprehens Canc Ctr, Sch Publ Hlth, Los Angeles, CA 90095 USA

[16] Great Plains Tribal Leaders Hlth Board, Community Hlth Prevent Programs, Rapid City, SD USA

[17] Harvard Med Sch, Massachusetts Gen Hosp, Div Hematol Oncol, Boston, MA USA

[18] Massachusetts Gen Hosp, Mongan Inst, Boston, MA USA

[19] Fight Colorectal Canc, 134 Pk Cent Sq Ste 210, Springfield, MO 65806 USA

来源：

CONTEMPORARY CLINICAL TRIALS | 2024年 / 145卷

关键词：

cancer screening; cancer prevention; multilevel intervention; equity; disparities; CLUSTER-RANDOMIZED-TRIAL; PATIENT NAVIGATION; SOCIOECONOMIC-STATUS; CARE; COLONOSCOPY; RISK; SYSTEM; BREAST; DISPARITIES; STRATEGIES;

D O I：

10.1016/j.cct.2024.107639

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Introduction: Colorectal cancer (CRC) screening utilization is low among low-income, uninsured, and minority populations that receive care in community health centers (CHCs). There is a need for evidence-based interventions to increase screening and follow-up care in these settings. Methods: A multilevel, multi-component pragmatic cluster randomized controlled trial is being conducted at 8 CHCs in two metropolitan areas (Boston and Los Angeles), with two arms: (1) Mailed FIT outreach with text reminders, and (2) Mailed FIT-DNA with patient support. We also include an additional CHC in Rapid City (South Dakota) that follows a parallel protocol for FIT-DNA but is not randomized due to lack of a comparison group. Eligible individuals in participating clinics are primary care patients ages 45-75, at average-risk for CRC, and overdue for CRC screening. Participants with abnormal screening results are offered navigation for follow-up colonoscopy and CRC risk assessment. Results: The primary outcome is the completion rate of CRC screening at 90 days. Secondary outcomes include the screening completion rate at 180 days and the rate of colonoscopy completion within 6 months among participants with an abnormal result. Additional goals are to enhance our understanding of facilitators and barriers to CRC risk assessment in CHC settings. Conclusions: This study assesses the effectiveness of two multilevel interventions to increase screening participation and follow-up after abnormal screening in under-resourced clinical settings, informing future efforts to address CRC disparities. Trial Registration: NCT05714644

引用

页数：7

共 63 条

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