Bridging the Divide: A Review on the Implementation of Personalized Cancer Medicine

被引:4
|
作者
Masucci, Michele [1 ,2 ]
Karlsson, Claes [3 ]
Blomqvist, Lennart [4 ]
Ernberg, Ingemar [2 ]
机构
[1] Karolinska Inst, Dept Learning Inforamt Management & Eth LIME, Tomtebodavagen 18B, Solna S-17165, Sweden
[2] Karolinska Inst, Dept Microbiol Tumor & Cell Biol MTC, Solnavagen 9, S-17165 Solna, Sweden
[3] Karolinska Inst, Dept Oncol Pathol Onc Pat, Anna Stecksens Gata 30A,D2 04, S-17165 Solna, Sweden
[4] Karolinska Inst, Dept Mol Med & Surg MMK, Anna Stecksens Gata 53, S-17165 Solna, Sweden
来源
JOURNAL OF PERSONALIZED MEDICINE | 2024年 / 14卷 / 06期
关键词
individualized medicine; precision medicine; personalized medicine; stratified medicine; translational cancer research; cancer care; oncology; evidence-based medicine; team science; organization; management; scientific leadership; CELL LUNG-CANCER; PRECISION MEDICINE; HEALTH-CARE; TEAM SCIENCE; TUMOR BOARD; FUTURE; CHALLENGES; ONCOLOGY; GENOMICS; HETEROGENEITY;
D O I
10.3390/jpm14060561
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
The shift towards personalized cancer medicine (PCM) represents a significant transformation in cancer care, emphasizing tailored treatments based on the genetic understanding of cancer at the cellular level. This review draws on recent literature to explore key factors influencing PCM implementation, highlighting the role of innovative leadership, interdisciplinary collaboration, and coordinated funding and regulatory strategies. Success in PCM relies on overcoming challenges such as integrating diverse medical disciplines, securing sustainable investment for shared infrastructures, and navigating complex regulatory landscapes. Effective leadership is crucial for fostering a culture of innovation and teamwork, essential for translating complex biological insights into personalized treatment strategies. The transition to PCM necessitates not only organizational adaptation but also the development of new professional roles and training programs, underscoring the need for a multidisciplinary approach and the importance of team science in overcoming the limitations of traditional medical paradigms. The conclusion underscores that PCM's success hinges on creating collaborative environments that support innovation, adaptability, and shared vision among all stakeholders involved in cancer care.
引用
收藏
页数:26
相关论文
共 50 条
  • [1] 'Personalized medicine': what's in a name?
    Pokorska-Bocci, Anna
    Stewart, Alison
    Sagoo, Gurdeep S.
    Hall, Alison
    Kroese, Mark
    Burton, Hilary
    PERSONALIZED MEDICINE, 2014, 11 (02) : 197 - 210
  • [2] Reproducing the normal and the pathological in personalized cancer medicine clinical trials
    Chorev, Nadav Even
    Filc, Dani
    BIOSOCIETIES, 2024,
  • [3] Personalized medicine: An alternative for cancer treatment
    Singh, Devendra
    Dhiman, Vinay Kumar
    Pandey, Minakshi
    Dhiman, Vivek Kumar
    Sharma, Avinash
    Pandey, Himanshu
    Verma, Sunil Kumar
    Pandey, Rajeev
    CANCER TREATMENT AND RESEARCH COMMUNICATIONS, 2024, 42
  • [4] Current landscape of personalized medicine adoption and implementation in Southeast Asia
    Chong, Huey Yi
    Allotey, Pascale A.
    Chaiyakunapruk, Nathorn
    BMC MEDICAL GENOMICS, 2018, 11
  • [5] Personalized Medicine in Gynecologic Cancer Fact or Fiction?
    Corey, Logan
    Valente, Ana
    Wade, Katrina
    SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, 2020, 29 (01) : 105 - +
  • [6] Personalized Medicine in Gynecologic Cancer Fact or Fiction?
    Corey, Logan
    Valente, Ana
    Wade, Katrina
    OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA, 2019, 46 (01) : 155 - +
  • [7] Health Information Technologies for Cancer Care: Characterizing Developments for Precision and Personalized Medicine
    Shah, Parth V.
    Ringland, Kathryn E.
    CONFERENCE COMPANION PUBLICATION OF THE 2019 COMPUTER SUPPORTED COOPERATIVE WORK AND SOCIAL COMPUTING (CSCW'19 COMPANION), 2019, : 362 - 366
  • [8] Big data for neuroscience in the context of predictive, preventive, and personalized medicine
    Bajinka, Ousman
    Ouedraogo, Serge Yannick
    Li, Na
    Zhan, Xianquan
    EPMA JOURNAL, 2025, 16 (01) : 17 - 35
  • [9] Bridging the Gaps in Personalized Medicine Value Assessment: A Review of the Need for Outcome Metrics across Stakeholders and Scientific Disciplines
    Bush, William S.
    Bailey, Jessica N. Cooke
    Beno, Mark F.
    Crawford, Dana C.
    PUBLIC HEALTH GENOMICS, 2019, 22 (1-2) : 16 - 24
  • [10] Introducing volume 14 of Personalized Medicine
    Price-Evans, Adam
    PERSONALIZED MEDICINE, 2017, 14 (01) : 1 - 3