Nano-nutraceuticals to Combat Oxidative Stress: Unlocking Newer Paradigms in Adjuvant Therapy

被引:1
作者
Pooja [1 ]
Pandey, Manisha [1 ]
Kumar, Tarun [1 ]
Goswami, Harsh [1 ]
Kumari, Rasna [1 ]
Kumari, Shivani [1 ]
Jain, Neha [2 ]
Gorain, Bapi [3 ]
Maurya, Pawan Kumar [4 ]
Chawla, Viney [5 ]
Chawla, Pooja A. [5 ]
机构
[1] Cent Univ Haryana, Dept Pharmaceut Sci, Mahendergarh 123031, India
[2] Amity Univ, Amity Inst Pharm, Dept Pharmaceut, Noida, India
[3] Birla Inst Technol, Dept Pharmaceut Sci & Technol, Ranchi 835215, Jharkhand, India
[4] Cent Univ Haryana, Dept Biochem, Mahendergarh, India
[5] BFUHS Univ, Univ Inst Pharmaceut Sci & Res, Faridkot 151203, Punjab, India
关键词
Nutraceutical; Antioxidant; Oxidative stress; Nanotechnolology; Reactive oxygen species; BENZIMIDAZOLE DERIVATIVES BEARING; ANGIOTENSIN-II TYPE-1; ALPHA-GLUCOSIDASE; BIOLOGICAL EVALUATION; MOLECULAR DOCKING; ANTIINFLAMMATORY DRUGS; DESIGN; ANTICANCER; ANTAGONISTS; RESISTANCE;
D O I
10.2174/0115680266300779240417104340
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Nutraceuticals are products that provide both nutritional and therapeutic benefits. These compounds can slow the aging process and provide physiological effects shielding individuals from acute and chronic diseases. People's interests have shifted from allopathic to Ayurvedic to nutraceuticals in recent years. These are often common dietary supplements that have drawn customers worldwide because of their high nutritional safety and lack of adverse effects when used for a long time. Although conventional dosage forms, including pills, tablets, and semi-solids, are still available, they nevertheless have poorer bioavailability, less stability, and less effectiveness for targeted delivery of bioactives. The use of effective nanocomplex systems as nano-antioxidants using nanotechnology has become a promising field. Among its many uses, nanotechnology is mostly used to create foods and nutraceuticals that are more bioavailable, less toxic, and more sustainable. Additionally, it has been emphasized how precisely nano-pharmaceuticals for oxidative stress produce the desired effects. These improvements show improved antioxidant delivery to the target region, reduced leakage, and increased targeting precision. The outcomes demonstrated that oxidative stress-related illnesses can be effectively treated by lowering ROS levels with the use of nanonutraceuticals. The major ideas and uses of nano-nutraceuticals for health are outlined in this review, with an emphasis on reducing oxidative stress.
引用
收藏
页码:1490 / 1503
页数:14
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