Structural and catalytic advancement of fungal tannase: A proteomic contribution in industrial applicability

Microbial enzymes are the global concern in the field of biotechnology. Tannase is an inducible microbial biocatalyst that catalyzes the bioconversion of tannins. It has wide application in the manufacture of gallic acid, pyrogallol, food and beverage processing, management of tannery effluents and wastewater. Fungi are treated as the most potential tannase producers as compared to bacteria. The present review is a compilation of information related to various aspects of fungal tannase including source organism, production, downstream processing, biochemical and molecular characterization with special reference to surface chemistry. Cloning and expression of fungal tannase genes and study of tannase structural architecture has provided the critical insight regarding stability and catalytic activity. In silico studies and metagenomic approaches in fungal tannase have also been included. Overall, it is an initiative with advanced report regarding the better understanding of stability and potentiality of fungal tannase towards industrial application.