Common Denominator of MASLD and Some Non-Communicable Diseases

被引:3
作者
Ferenc, Katarzyna [1 ]
Jarmakiewicz-Czaja, Sara [2 ]
Sokal-Dembowska, Aneta [2 ]
Stasik, Katarzyna [1 ,3 ]
Filip, Rafal [1 ,3 ]
机构
[1] Rzeszow Univ, Inst Med, Med Coll, PL-35959 Rzeszow, Poland
[2] Rzeszow Univ, Inst Hlth Sci, Med Coll, PL-35959 Rzeszow, Poland
[3] Clin Hosp 2, Dept Gastroenterol, IBD Unit, PL-35301 Rzeszow, Poland
关键词
cardiovascular diseases; diabetes; liver cancer; obesity; steatotic liver disease; FATTY LIVER-DISEASE; INSULIN-RESISTANCE; HEPATOCELLULAR-CARCINOMA; CARDIOVASCULAR RISK; HEPATIC STEATOSIS; DIETARY FRUCTOSE; GUT MICROBIOME; OBESITY; CANCER; NAFLD;
D O I
10.3390/cimb46070399
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Currently, steatohepatitis has been designated as metabolic dysfunction-associated steatohepatitis (MASLD). MASLD risk factors mainly include metabolic disorders but can also include genetic, epigenetic, and environmental factors. Disease entities such as obesity, diabetes, cardiovascular disease, and MASLD share similar pathomechanisms and risk factors. Moreover, a bidirectional relationship is observed between the occurrence of certain chronic diseases and MASLD. These conditions represent a global public health problem that is responsible for poor quality of life and high mortality. It seems that paying holistic attention to these problems will not only help increase the chances of reducing the incidence of these diseases but also assist in the prevention, treatment, and support of patients.
引用
收藏
页码:6690 / 6709
页数:20
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