Immunocompetence against gastrointestinal nematodes and its genetic improvement in sheep-1. Infection, immunological response and immunity

被引:0
作者
Schmid, Markus [1 ]
Bennewitz, Joern [1 ]
Stefanski, Volker [1 ]
机构
[1] Univ Hohenheim, Inst Nutztierwissenschaften, Garbenstr 17, D-70599 Stuttgart, Germany
来源
ZUCHTUNGSKUNDE | 2024年 / 96卷 / 04期
关键词
Endoparasite infection; immune system; parasite-host interaction; pasture sheep farming; WORM EGG COUNT; HAEMONCHUS-CONTORTUS; ANTHELMINTIC RESISTANCE; PARAMETERS; PARASITES; TELADORSAGIA; PREVALENCE; REDUCTION; DIARRHEA; PROTEIN;
D O I
暂无
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
On pasture, sheep are exposed to infections with gastrointestinal nematodes. Infections with gastrointestinal nematodes cause damage to the animal and also have economic relevance. In order to avoid an excessive parasite load in the animal and to treat parasitosis, anthelmintics are used for deworming. However, gastrointestinal nematodes are becoming increasingly resistant to anthelmintics, making treatment less and less effective. Accordingly, alternative strategies are required to combat gastrointestinal nematodes. Breeding sheep with increased immunocompetence against gastrointestinal nematodes is a sustainable and long-term strategy. In order to proceed responsibly and effectively, the complexity of infections with gastrointestinal nematodes must be considered in more detail. This review article therefore deals with the infection, the effects of the infection on the animal, the immunological response shown by the animal, the acquired immunity to gastrointestinal nematodes as well as with parasite-host interactions. The article refers to the situation in Germany and concludes with a summary of the need for national action.
引用
收藏
页码:312 / 327
页数:16
相关论文
共 66 条
[1]   Immunoglobulins as Biomarkers for Gastrointestinal Nematodes Resistance in Small Ruminants: A systematic review [J].
Aboshady, H. M. ;
Stear, M. J. ;
Johansson, A. ;
Jonas, E. ;
Bambou, J. C. .
SCIENTIFIC REPORTS, 2020, 10 (01)
[3]   Immune Responses Associated with Resistance to Haemonchosis in Sheep [J].
Alba-Hurtado, Fernando ;
Antonio Munoz-Guzman, Marco .
BIOMED RESEARCH INTERNATIONAL, 2013, 2013
[4]   Differences in immune responses to Haemonchus contortus infection in the susceptible Ile de France and the resistant Santa Ines sheep under different anthelmintic treatments regimens [J].
Albuquerque, Ana Claudia A. ;
Bassetto, Cesar Cristiano ;
Almeida, Fabiana A. ;
Hildersley, Katie A. ;
McNeilly, Tom N. ;
Britton, Collette ;
Amarante, Alessandro F. T. .
VETERINARY RESEARCH, 2019, 50 (01)
[5]   Deep amplicon sequencing as a powerful new tool to screen for sequence polymorphisms associated with anthelmintic resistance in parasitic nematode populations [J].
Avramenko, Russell W. ;
Redman, Elizabeth M. ;
Melville, Lynsey ;
Bartley, Yvonne ;
Wit, Janneke ;
Queiroz, Camila ;
Bartley, Dave J. ;
Gilleard, John S. .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2019, 49 (01) :13-26
[6]   Local and systemic immune mediators of Morada Nova lambs with divergentHaemonchus contortusresistance phenotypes [J].
Barbosa Toscano, Joao Henrique ;
Okino, Cintia Hiromi ;
Barbosa dos Santos, Isabella ;
Giraldelo, Luciana Aparecida ;
Borsch von Haehling, Marei ;
Novita Esteves, Sergio ;
Bassetto, Cesar Cristiano ;
Talamini do Amarante, Alessandro Francisco ;
de Souza Chagas, Ana Carolina .
PARASITE IMMUNOLOGY, 2020, 42 (12)
[7]   Wild ruminants as reservoirs of domestic livestock gastrointestinal nematodes [J].
Barone, Carly D. ;
Wit, Janneke ;
Hoberg, Eric P. ;
Gilleard, John S. ;
Zarlenga, Dante S. .
VETERINARY PARASITOLOGY, 2020, 279
[8]   The periparturient relaxation of immunity in Merino ewes infected with Trichostrongylus colubriformis: Parasitological and immunological responses [J].
Beasley, A. M. ;
Kahn, L. P. ;
Windon, R. G. .
VETERINARY PARASITOLOGY, 2010, 168 (1-2) :60-70
[9]   Generalist nematodes dominate the nemabiome of roe deer in sympatry with sheep at a regional level [J].
Beaumelle, Camille ;
Redman, Elizabeth ;
Verheyden, Helene ;
Jacquiet, Philippe ;
Begoc, Noemie ;
Veyssiere, Florence ;
Benabed, Slimania ;
Cargnelutti, Bruno ;
Lourtet, Bruno ;
Poirel, Marie-Therese ;
de Rijke, Jill ;
Yannic, Glenn ;
Gilleard, John S. ;
Bourgoin, Gilles .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2022, 52 (12) :751-761
[10]  
Bellof G., 2019, Schaf- und Ziegenfutterung