Autoimmune thrombotic thrombocytopenic purpura associated with disseminated sarcoidosis: A case report

被引：0

作者：

Billotte, Maxime ^{[1
]}

Eszto, Peter ^{[2
]}

Thomas, Benoit ^{[3
]}

Groizard, Pierre ^{[4
]}

Perez, Pierre ^{[5
]}

Campagne, Julien ^{[1
,6
]}

机构：

[1] Hop Robert Schuman, Med Interne, Vantoux, France

[2] Hop Robert Schuman, Reanimat, Vantoux, France

[3] Hop Robert Schuman, Lab Biol Med, Vantoux, France

[4] Hop Instruct Armees Legouest, Med Interne & Rhumatol, Metz, France

[5] Univ Lorraine, Ctr Hosp Reg Univ Nancy, Med Intens & Reanimat, Nancy, France

[6] Hop Robert Schuman, Rue Champ Montoy, F-57070 Vantoux, France

来源：

EJHAEM | 2024年 / 5卷 / 01期

关键词：

ADAMTS13; antibodies; case report; sarcoidosis; thrombotic thrombocytopenic purpura; MICROANGIOPATHY; DISEASES;

D O I：

10.1002/jha2.848

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sarcoidosis is an inflammatory disease known to be associated with multiple autoimmune disorders. There is a restricted number of descriptions of the association between sarcoidosis and autoimmune thrombotic thrombocytopenic purpura (aTTP). We present the case of a 63-year-old woman admitted to the hospital to investigate a possible sarcoidosis who had hemolytic anemia and thrombocytopenia, with low ADAMTS13 activity and anti-ADAMTS13 antibodies, leading to a diagnosis of aTTP. Sarcoidosis was later confirmed and the two conditions evolved separately after 6 months, questioning the link between them. Clinicians should be aware of this rare cause of thrombocytopenia in patients with sarcoidosis, as aTTP is a life-threatening condition.

引用

页码：225 / 230

页数：6

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