Prevotella enterotype associates with diets supporting acidic faecal pH and production of propionic acid by microbiota

被引：9
作者：
Adamberg, Signe [1 ]
Adamberg, Kaarel [1 ,2 ,3 ]
机构：
[1] Tallinn Univ Technol, Dept Chem & Biotechnol, EE-12618 Tallinn, Estonia
[2] Ctr Food & Fermentat Technol, EE-12618 Tallinn, Estonia
[3] Akad tee 15, EE-12618 Tallinn, Estonia
来源：
HELIYON | 2024年 / 10卷 / 10期
关键词：
Gut microbiota; Food diary; Faecal pH; Short chain fatty acids (SCFA); Enterotypes; CHAIN FATTY-ACIDS; GUT MICROBIOTA; RESISTANT STARCH; WHEAT BRAN; FERMENTATION; BUTYRATE; INDEXES; HEALTH; BULK;
D O I：
10.1016/j.heliyon.2024.e31134
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Metabolism of dietary fibres by colon microbiota plays an important role for human health. Personal data from a nutrition study (57 subjects) were analysed to elucidate quantitative associations between the diet, faecal microbiome, organic acid concentrations and pH. Ratios of the predominant acids acetate, butyrate and propionate ranged from 1:0.67:0.27 to 1:0.17:0.36. Pectin-rich diets resulted in higher faecal acetate concentrations. Negative correlation between faecal pH and BSS was observed. Higher faecal pH and lower acid concentrations were related to the higher abundance of amino acid degrading Clostridium, Odoribacter and Eubacterium coprostanoligenes, which are weak carbohydrate fermenting taxa. Propionic acid correlated especially to high abundance of Prevotella and low abundance of proteobacteria. The acetate to propionate ratio of the Prevotella enterotype was about half of that of the Bacteroides enterotype. Based on the results we suggest the measurement of faecal pH and organic acid composition for research and diagnostic purposes.
引用
收藏
页数：12
相关论文
共 46 条
[1]   Use of Changestat for Growth Rate Studies of Gut Microbiota [J].
Adamberg, Kaarel ;
Raba, Grete ;
Adamberg, Signe .
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 8
[2]   The composition of faecal microbiota is related to the amount and variety of dietary fibres [J].
Adamberg, Kaarel ;
Jaagura, Madis ;
Aaspollu, Anu ;
Nurk, Eha ;
Adamberg, Signe .
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 2020, 71 (07) :845-855
[3]   Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions [J].
Baldini, Federico ;
Hertel, Johannes ;
Sandt, Estelle ;
Thinnes, Cyrille C. ;
Neuberger-Castillo, Lorieza ;
Pavelka, Lukas ;
Betsou, Fay ;
Krueger, Rejko ;
Thiele, Ines .
BMC BIOLOGY, 2020, 18 (01)
[4]   Wholegrain foods made from a novel high-amylose barley variety (Himalaya 292) improve indices of bowel health in human subjects [J].
Bird, Anthony R. ;
Vuaran, Michelle S. ;
King, Roger A. ;
Noakes, Manny ;
Keogh, Jennifer ;
Morell, Matthew K. ;
Topping, David L. .
BRITISH JOURNAL OF NUTRITION, 2008, 99 (05) :1032-1040
[5]   Almond consumption affects fecal microbiota composition, stool pH, and stool moisture in overweight and obese adults with elevated fasting blood glucose: A randomized controlled trial [J].
Choo, Jocelyn M. ;
Tran, Cuong D. ;
Luscombe-Marsh, Natalie D. ;
Stonehouse, Welma ;
Bowen, Jane ;
Johnson, Nathan ;
Thompson, Campbell H. ;
Watson, Emma-Jane ;
Brinkworth, Grant D. ;
Rogers, Geraint B. .
NUTRITION RESEARCH, 2021, 85 :47-59
[6]   Modulation of the human gut microbiota by dietary fibres occurs at the species level [J].
Chung, Wing Sun Faith ;
Walker, Alan W. ;
Louis, Petra ;
Parkhill, Julian ;
Vermeiren, Joan ;
Bosscher, Douwina ;
Duncan, Sylvia H. ;
Flint, Harry J. .
BMC BIOLOGY, 2016, 14
[7]   THE CONTROL AND CONSEQUENCES OF BACTERIAL FERMENTATION IN THE HUMAN COLON [J].
CUMMINGS, JH ;
MACFARLANE, GT .
JOURNAL OF APPLIED BACTERIOLOGY, 1991, 70 (06) :443-459
[8]   The role of short-chain fatty acids in microbiota-gut-brain communication [J].
Dalile, Boushra ;
Van Oudenhove, Lukas ;
Vervliet, Bram ;
Verbeke, Kristin .
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2019, 16 (08) :461-478
[9]   High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome [J].
De Filippis, Francesca ;
Pellegrini, Nicoletta ;
Vannini, Lucia ;
Jeffery, Ian B. ;
La Storia, Antonietta ;
Laghi, Luca ;
Serrazanetti, Diana I. ;
Di Cagno, Raffaella ;
Ferrocino, Ilario ;
Lazzi, Camilla ;
Turroni, Silvia ;
Cocolin, Luca ;
Brigidi, Patrizia ;
Neviani, Erasmo ;
Gobbetti, Marco ;
O'Toole, Paul W. ;
Ercolini, Danilo .
GUT, 2016, 65 (11) :1812-1821
[10]   Akkermansia muciniphila and its role in regulating host functions [J].
Derrien, Muriel ;
Belzer, Clara ;
de Vos, Willem M. .
MICROBIAL PATHOGENESIS, 2017, 106 :171-181
12345