Advancements and challenges in brain cancer therapeutics

被引:7
作者
Bai, Fan [1 ,2 ]
Deng, Yueyang [3 ,4 ]
Li, Long [1 ,5 ]
Lv, Ming [6 ]
Razzokov, Jamoliddin [7 ,8 ,9 ]
Xu, Qingnan [1 ]
Xu, Zhen [1 ]
Chen, Zhaowei [10 ]
Chen, Guojun [3 ,4 ]
Chen, Zhitong [1 ,2 ,5 ,11 ]
机构
[1] Chinese Acad Sci, Paul C Lauterbur Res Ctr Biomed Imaging, Inst Biomed & Hlth Engn, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China
[2] Natl Innovat Ctr Adv Med Devices, Adv Therapeut Ctr, Shenzhen, Peoples R China
[3] McGill Univ, Dept Biomed Engn, Montreal, PQ H3G 0B1, Canada
[4] McGill Univ, Rosalind & Morris Goodman Canc Inst, Montreal, PQ, Canada
[5] Univ Chinese Acad Sci, Shenzhen, Guangdong, Peoples R China
[6] Chinese Peoples Liberat Army Gen Hosp, Dept Med Engn, Med Supplies Ctr, Beijing, Peoples R China
[7] Natl Res Univ TIIAME, Inst Fundamental & Appl Res, Tashkent, Uzbekistan
[8] Ctr Adv Technol, Lab Expt Biophys, Tashkent, Uzbekistan
[9] Tashkent State Tech Univ, Dept Biomed Engn, Tashkent, Uzbekistan
[10] Fuzhou Univ, Inst Food Safety & Environm Monitoring, Coll Chem, MOE Key Lab Analyt Sci Food Safety & Biol, Fuzhou, Peoples R China
[11] Chinese Acad Sci, Key Lab Biomed Imaging Sci & Syst, Shenzhen, Peoples R China
来源
EXPLORATION | 2024年 / 4卷 / 06期
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
brain tumor; cold atmospheric plasma therapy; radiotherapy; TUMOR-TREATING FIELDS; COLD ATMOSPHERIC PLASMA; GAMMA-KNIFE RADIOSURGERY; PHOTODYNAMIC THERAPY PDT; FRACTIONATED STEREOTACTIC RADIOTHERAPY; INTERSTITIAL THERMAL THERAPY; DRUG-DELIVERY SYSTEMS; HIGH-GRADE GLIOMAS; CELL LUNG-CANCER; MICROWAVE ABLATION;
D O I
10.1002/EXP.20230177
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Treating brain tumors requires a nuanced understanding of the brain, a vital and delicate organ. Location, size, tumor type, and surrounding tissue health are crucial in developing treatment plans. This review comprehensively summarizes various treatment options that are available or could be potentially available for brain tumors, including physical therapies (radiotherapy, ablation therapy, photodynamic therapy, tumor-treating field therapy, and cold atmospheric plasma therapy) and non-physical therapies (surgical resection, chemotherapy, targeted therapy, and immunotherapy). Mechanisms of action, potential side effects, indications, and latest developments, as well as their limitations, are highlighted. Furthermore, the requirements for personalized, multi-modal treatment approaches in this rapidly evolving field are discussed, emphasizing the balance between efficacy and patient safety. The review summarizes various treatment options for brain tumors, focusing on their mechanisms, potential side effects, and recent developments. It emphasizes the need for personalized, multi-modal treatment approaches in this rapidly evolving field, balancing efficacy and patient safety. The complexity and diversity of brain tumor treatments are highlighted, advocating for ongoing research and technological advancements to improve patient outcomes. image
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页数:42
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