Fractionation schemes in adjuvant radiotherapy for breast cancer: review of the evidence and therapeutic approach at the National Institute of Cancerology, Colombia

Radiotherapy is a fundamental component in the management of breast cancer, particularly in the adjuvant setting, as its benefits in the treatment of breast cancer in terms of local recurrence, disease -free survival, and overall survival have been widely demonstrated. Hypofractionated radiation schedules are the current standard of adjuvant treatment in patients with early -stage breast cancer. Thus, the Radiation Oncology Unit and the Functional Unit for Breast and Soft Tissue Tumors of the Instituto Nacional de Cancerologia (INC) (Bogota, Colombia) decided to review the evidence on the subject and establish indications for different hypofractionation schemes at the INC, both for patients with cancers in early stages and for those with locally advanced tumors.