Outcome of stroke patients eligible to mechanical thrombectomy managed by spoke center, primary stroke center or comprehensive stroke center in the East of France

被引:0
作者
Abou Loukoul, W. [1 ]
Richard, S. [2 ,3 ]
Mione, G. [2 ]
Finitsis, S. [4 ]
Derelle, A. -L [1 ]
Zhu, F. [1 ,5 ]
Liao, L. [1 ]
Anxionnat, R. [1 ,5 ]
Douarinou, M. [1 ,2 ]
Humbertjean, L. [2 ]
Gory, B. [1 ]
机构
[1] CHRU Nancy, Hop Cent, Dept Diagnost & Therapeut Neuroradiol, 29 Ave Marechal Delattre Detassigny, F-54035 Nancy, France
[2] CHRU Nancy, Dept Neurol, Stroke Unit, Nancy, France
[3] Univ Lorraine, Inserm, U1116, Nancy, France
[4] Aristotle Univ Thessaloniki, Ahepa Hosp, Thessaloniki, Greece
[5] Univ Lorraine, Inserm, U1254, Nancy, France
关键词
Outcome; Stroke; Large vessel occlusion; Mechanical thrombectomy; Spoke center; Primary stroke center; Comprehensive stroke center; LARGE VESSEL OCCLUSION; ISCHEMIC-STROKE; ENDOVASCULAR THROMBECTOMY; TRIAL; THROMBOLYSIS; ALTEPLASE;
D O I
10.1016/j.neurol.2023.08.020
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and purpose. - Patients with suspected stroke are referred to the nearest hospital and are managed either in a spoke center (SC), a primary stroke center (PSC), or a comprehensive stroke center (CSC) in order to benefit from early intravenous thrombolysis (IVT). In case of large vessel occlusion (LVO), mechanical thrombectomy (MT) is only performed in the CSC, whereas the effectiveness of MT is highly time-dependent. There is a debate about the best management model of patients with suspected LVO. Therefore, we aimed to compare functional and safety outcomes of LVO patients eligible for MT managed through our regional telestroke system. Method. - We performed a retrospective analysis of our observational prospective clinical registry in all consecutive subjects with LVO within six hours of onset who were admitted to the SC, PSC, or CSC in the east of France between October 2017 and November 2022. The primary endpoint was the functional independence defined as modified Rankin scale (mRS) score 0 to 2 at 90 days. Secondary endpoints were functional outcome, early neurological improvement, symptomatic intracranial hemorrhage and 90-day mortality. Results. - Among the 794 included patients with LVO who underwent MT, 122 (15.4%) were managed by a SC, 403 (50.8%) were first admitted to a PSC, and 269 (33.9%) were first admitted to the CSC. The overall median NIHSS and ASPECTS score were 16 and 8, respectively.
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页码:517 / 523
页数:7
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