Modulation of Endothelial Cell Mitochondrial Phenotype and Angiogenesis by TRPV4

被引:0
|
作者
Dalal, Kesha
Katari, Venkatesh
Kondapalli, Narendra
Paruchuri, Sailala
Thodeti, Charles
机构
基金
美国国家卫生研究院;
关键词
TRPV4; mitochondria; dynamics; mechanical signals; morphology; OCR; MYLS22;
D O I
10.1152/physiol.2024.39.S1.660
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Regulation of endothelial cell mitochondrial phenotype by mechanosensitive ion channel TRPV4
    Dalal, Kesha
    Katari, Venkatesh
    Paruchuri, Sailaja
    Thodeti, Charles
    PHYSIOLOGY, 2023, 38
  • [2] TRPV4 channels regulate tumor angiogenesis through the modulation of Rho-dependent tumor endothelial cell mechanosensitivity
    Thodeti, Charles K.
    Adapala, Ravi K.
    Ghosh, Kaustabh
    Thoppil, Roslin
    Dudley, Andrew C.
    Klagsbrun, Michael
    Chilian, William
    Ingber, Donald
    FASEB JOURNAL, 2012, 26
  • [3] Extracellular Vesicles From Pathological Microenvironment Induce Endothelial Cell Transformation and Abnormal Angiogenesis via Modulation of TRPV4 Channels
    Guarino, Brianna D.
    Adapala, Ravi K.
    Kanugula, Anantha K.
    Lenkey, Nina M.
    Dougherty, Julie A.
    Paruchuri, Sailaja
    Khan, Mahmood
    Thodeti, Charles K.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2019, 7
  • [4] Endothelial Trpv4 Contributes to Pressure Overload-induced Pathological Hypertrophy via Modulation of Coronary Angiogenesis
    Adapala, Ravi K.
    Kanugula, Anantha K.
    Ohanyan, Vahagn A.
    Paruchuri, Sailaja M.
    Chilian, William M.
    Thodeti, Charles K.
    CIRCULATION RESEARCH, 2020, 127 (12) : E274 - E275
  • [5] Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity
    Kanugula, Anantha K.
    Adapala, Ravi K.
    Jamaiyar, Anurag
    Lenkey, Nina
    Guarino, Brianna D.
    Liedtke, Wolfgang
    Yin, Liya
    Paruchuri, Sailaja
    Thodeti, Charles K.
    ANGIOGENESIS, 2021, 24 (03) : 647 - 656
  • [6] Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity
    Anantha K. Kanugula
    Ravi K. Adapala
    Anurag Jamaiyar
    Nina Lenkey
    Brianna D. Guarino
    Wolfgang Liedtke
    Liya Yin
    Sailaja Paruchuri
    Charles K. Thodeti
    Angiogenesis, 2021, 24 : 647 - 656
  • [7] TRPV4 Channels Regulate Tumor Angiogenesis via Modulation of ERK1/2-DependentTumor Endothelial Cell Proliferation
    Thoppil, Roslin
    Adapala, Ravi
    Cappelli, Holly
    Paruchuri, Sailaja
    Meszaros, J. Gary
    Thodeti, Charles
    FASEB JOURNAL, 2015, 29
  • [8] Modulation of TRPV4 by diverse mechanisms
    Darby, W. G.
    Grace, M. S.
    Baratchi, S.
    McIntyre, P.
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2016, 78 : 217 - 228
  • [9] Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis
    O'Leary, Caitriona
    McGahon, Mary K.
    Ashraf, Sadaf
    McNaughten, Jennifer
    Friedel, Thomas
    Cincola, Patrizia
    Barabas, Peter
    Fernandez, Jose A.
    Stitt, Alan W.
    McGeown, J. Graham
    Curtis, Tim M.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (10) : 3297 - 3309
  • [10] Extracellular vesicles from tumor microenvironment transforms endothelial cell phenotype via downregulation of TRPV4 channels
    Guarino, Brianna
    Adapala, Ravi
    Kanugula, Anantha
    Dougherty, Julie
    Paruchuri, Sailaja
    Mahmood, Khan
    Thodeti, Charles
    FASEB JOURNAL, 2020, 34