INVESTIGATION OF THE MECHANICAL PROPERTIES OF ADDITIVELY MANUFACTURED BONE TISSUE SCAFFOLDS, COMPOSED OF POLYAMIDE, POLYOLEFIN, AND CELLULOSE FIBERS

被引:0
作者
Mandava, Paavana Krishna [1 ]
Joyce, Robert [2 ]
Day, James B. [3 ]
Salary, Roozbeh [4 ,5 ]
机构
[1] Marshall Univ, CECS, Dept Mech Engn, Huntington, WV 25755 USA
[2] FibreTuff Biotechnol Co, Toledo, OH 43615 USA
[3] Marshall Univ, Sch Med, Dept Orthopaed Surg, Huntington, WV 25701 USA
[4] Marshall Univ, Dept Mech Engn, Huntington, WV 25755 USA
[5] Marshall Univ, Dept Biomed Engn, Huntington, WV 25755 USA
来源
PROCEEDINGS OF ASME 2022 17TH INTERNATIONAL MANUFACTURING SCIENCE AND ENGINEERING CONFERENCE, MSEC2022, VOL 1 | 2022年
关键词
Additive Manufacturing; Material Extrusion; Bone Scaffold; Regenerative Medicine; Triply Periodic Minimal Surface (TPMS); FibreTuff; FABRICATION;
D O I
暂无
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The goal of this research work is to fabricate mechanically robust, porous, and biocompatible bone scaffolds with textured surfaces (for cell/tissue adhesion) for the treatment of osseous fractures. The objective of the work is to investigate the mechanical properties of triply periodic minimal surface (TPMS) bone scaffolds, fabricated using fused deposition modeling (FDM) additive manufacturing process, based on a medical grade composite composed of polyamide, polyolefin, and cellulose fibers. FDM has emerged as a high-resolution method for the fabrication of biological tissues and constructs. FDM allows for non-contact, multi-material deposition of functional materials for tissue engineering applications. However, the FDM process is intrinsically complex; the complexity of the process, largely, stems from complex physical phenomena and material-process interactions, which may adversely influence the mechanical properties, the surface morphology, and ultimately the functional characteristics of fabricated bone scaffolds. Consequently, physics-based material and process characterization would be an inevitable need. In this study, seven TPMS bone scaffolds were fabricated, based on the medical-grade polymer composite. The compression properties of the fabricated bone scaffolds were measured using a compression testing machine. The outcomes of this study pave the way for the fabrication of complex composite bone scaffolds with tunable medical and functional properties.
引用
收藏
页数:6
相关论文
共 15 条
  • [1] Development and characterization of a PLGA-HA composite material to fabricate 3D-printed scaffolds for bone tissue engineering
    Babilotte, Joanna
    Martin, Benoit
    Guduric, Vera
    Bareille, Reine
    Agniel, Remy
    Roques, Samantha
    Heroguez, Valerie
    Dussauze, Marc
    Gaudon, Manuel
    Le Nihouannen, Damien
    Catros, Sylvain
    [J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2021, 118
  • [2] Chaffins A, 2021, PROCEEDINGS OF THE ASME 2021 16TH INTERNATIONAL MANUFACTURING SCIENCE AND ENGINEERING CONFERENCE (MSEC2021), VOL 1
  • [3] Fabrication and properties of poly(vinyl alcohol)/β-tricalcium phosphate composite scaffolds via fused deposition modeling for bone tissue engineering
    Chen, Gang
    Chen, Ning
    Wang, Qi
    [J]. COMPOSITES SCIENCE AND TECHNOLOGY, 2019, 172 : 17 - 28
  • [4] Highly loaded hydroxyapatite microsphere/PLA porous scaffolds obtained by fused deposition modelling
    Corcione, Carola Esposito
    Gervaso, Francesca
    Scalera, Francesca
    Padmanabhan, Sanosh Kunjalukkal
    Madaghiele, Marta
    Montagna, Francesco
    Sannino, Alessandro
    Licciulli, Antonio
    Maffezzoli, Alfonso
    [J]. CERAMICS INTERNATIONAL, 2019, 45 (02) : 2803 - 2810
  • [5] E3D, V6 Assembly," C. Open Source Creative Commons CC BY-SA 3.0 License
  • [6] Additive manufacturing of bioceramic scaffolds by combination of FDM and slip casting
    Esslinger, Steffen
    Gadow, Rainer
    [J]. JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2020, 40 (11) : 3707 - 3713
  • [7] Development of controlled porosity polymer-ceramic composite scaffolds via fused deposition modeling
    Kalita, SJ
    Bose, S
    Hosick, HL
    Bandyopadhyay, A
    [J]. MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2003, 23 (05): : 611 - 620
  • [8] Klemstine C., 2021, ASME INT MECH ENG C
  • [9] 3D printing and morphological characterisation of polymeric composite scaffolds
    Oladapo, Bankole, I
    Ismail, Sikiru O.
    Zahedi, Mohsen
    Khan, Affan
    Usman, Hazrat
    [J]. ENGINEERING STRUCTURES, 2020, 216
  • [10] 3D-printed PLA/HA composite structures as synthetic trabecular bone: A feasibility study using fused deposition modeling
    Wu, Dan
    Spanou, Andrea
    Diez-Escudero, Anna
    Persson, Cecilia
    [J]. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2020, 103 (103)