Unveiling the potential of Satureja calamintha nepeta: A study on its phytochemical composition and antibacterial activity

被引:0
作者
Hayani, Mouhcine [1 ]
Benabbouha, Tariq [2 ,7 ]
Nachit, Wafaa [3 ]
Byadi, Said [4 ]
Chefira, Khalil [5 ]
Aboulmouhajir, Aziz [4 ]
Tounsi, Abdessamad [6 ]
Zair, Touriya [1 ]
机构
[1] Univ Moulay Ismail, Fac Sci, Meknes, Morocco
[2] Univ Chouaib Doukkali, Analyt Fac Sci, Lab Chem Coordinat, El Jadida, Morocco
[3] Chouaib Doukkali Univ, Natl Sch Appl Sci ENSAJ, LabSIPE, El Jadida, Morocco
[4] Univ Hassan 2, Sci Fac Ain Chock, Organ Synth Extract & Valorizat Lab, Casablanca, Morocco
[5] Chouaib Doukkali Univ, Fac Sci, Lab Chem Coordinat & Analyt, El Jadida, Morocco
[6] Univ Sultan Moulay Slimane, Environm Ecol & Agroind Engn Lab, Beni Mellal, Morocco
[7] Univ Chouaib Doukkali, Fac Sci, Lab Chem Coordinat & Analyt, Team Thermodynam Surfaces & Catalysis, El Jadida 24000, Morocco
关键词
antibacterial activities; essential oil; GC-MS analysis; molecular docking; Satureja calamintha nepeta; ESSENTIAL OILS; CHEMICAL-COMPOSITION; MONTANA L; VIRULENCE; PARADIGM; OREGANO;
D O I
10.1002/vjch.202300174
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Satureja calamintha nepeta is a plant native to northwestern Morocco. The purpose of this investigation is to identify the chemical composition and evaluate the antibacterial of the essential oil extracted from this plant. Firstly, a quality inspection of the plant was carried out to quantify its level of metals, especially the heavier ones, using the ICP technique. Gas chromatography/mass spectrometry was used to characterize the chemical composition of essential oil. The chromatogram analysis shows the presence of 27 compounds, that is, 99.2% of the essential oil, with 1,8-cineole (34.34%) and cis-pinocamphone (11.87%) being the most significant. The antibacterial effectiveness of the essential oil was tested using the disc diffusion method against 6 gram-positive and gram-negative pathogens. The essential oil shows strong activity against Escherichia coli and Escherichia vekanda strains, with an MIC value of about 2.80 mu g/mL. The authors were benefited from the modeling technique to better understand the antibacterial activity.
引用
收藏
页码:772 / 779
页数:8
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