Multiple Painless Cervical Lymphadenopathies Misleading the Diagnosis of Kikuchi's Disease

被引:0
作者
Apandi, Afena [1 ,2 ]
Mansor, Wan Nabila Wan [1 ,2 ]
Musa, Zalilah [3 ]
Ali, Nurul Atiah Mohd [4 ]
机构
[1] Univ Kebangsaan Malaysia, Fac Med, Dept Otorhinolaryngol Head & Neck Surg, Kuala Lumpur, Malaysia
[2] Hosp Canselor Tuanku Muhriz, Dept Otorhinolaryngol Head & Neck Surg, Kuala Lumpur, Malaysia
[3] Hosp Sultanah Nur Zahirah, Dept Otorhinolaryngol, Kuala Terengganu, Malaysia
[4] Hosp Sultanah Nur Zahirah, Dept Pathol, Kuala Terengganu, Malaysia
关键词
leukopenia; neck; fever; lymphadenopathy; lymph node; biopsy; histiocyte necrotizing lymphadenitis; kikuchi's disease; FUJIMOTO-DISEASE; LYMPHADENITIS;
D O I
10.7759/cureus.58151
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Kikuchi's disease is an unusual and self-limited disease. It manifests as a painful cervical lymphadenopathy and is associated with a low-grade fever and night sweats. Recently, this disease has been reported worldwide, compared to its initial high prevalence among the Japanese population. The etiologies of Kikuchi's disease are still unknown, but it has been proposed to have either infectious or immunological causes. We report the atypical presentation of a young male with Kikuchi's disease. A 22-year-old male presented with a prolonged fever for a week, which was associated with bilateral neck swelling that was painless and gradually increased in size. In our case, histopathological examination of the left cervical lymph node revealed histiocytic necrotizing lymphadenitis in favor of Kikuchi's disease. This case report will highlight the atypical clinical presentation of this patient, thereby increasing awareness of the disease's future manifestation.
引用
收藏
页数:4
相关论文
共 11 条
[1]   Enigmatic Kikuchi-Fujimoto disease a comprehensive review [J].
Bosch, X ;
Guilabert, A ;
Miquel, R ;
Campo, E .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2004, 122 (01) :141-152
[2]   Kikuchi-Fujimoto disease [J].
Bosch, Xavier ;
Guilabert, Antonio .
ORPHANET JOURNAL OF RARE DISEASES, 2006, 1 (1)
[3]  
CHAN JKC, 1989, CANCER-AM CANCER SOC, V63, P1856
[4]   Kikuchi-Fujimoto disease [J].
Dalton, Julian ;
Shaw, Robert ;
Democratis, Jane .
LANCET, 2014, 383 (9922) :1098-1098
[5]  
DORFMAN RF, 1987, ARCH PATHOL LAB MED, V111, P1026
[6]   Fever of unknown origin in adults: 40 years on [J].
Knockaert, DC ;
Vanderschueren, S ;
Blockmans, D .
JOURNAL OF INTERNAL MEDICINE, 2003, 253 (03) :263-275
[7]   Kikuchi's disease: A review and analysis of 61 cases [J].
Lin, HC ;
Su, CY ;
Huang, CC ;
Hwang, CF ;
Chien, CY .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2003, 128 (05) :650-653
[8]   The fine needle aspiration appearances of Kikuchi's lymphadenitis [J].
Osborn, M. ;
Aqel, N. ;
Levine, T. S. .
CYTOPATHOLOGY, 2009, 20 (01) :36-43
[9]   Kikuchi-Fujimoto Disease A Review [J].
Perry, Anamarija M. ;
Choi, Sarah M. .
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2018, 142 (11) :1341-1346
[10]   Kikuchi-Fujimoto lymphadenitis: role of parvovirus B-19, Epstein-Barr virus, human herpesvirus 6, and human herpesvirus 8 [J].
Rosado, Flavia Guimaraes Nunes ;
Tang, Yi-Wei ;
Hasserjian, Robert Paul ;
McClain, Colt M. ;
Wang, Beverly ;
Mosse, Claudio A. .
HUMAN PATHOLOGY, 2013, 44 (02) :255-259