Trastuzumab-induced toxic epidermal necrolysis in a Her-2-positive metastatic breast cancer patient-A rare case report

被引:0
|
作者
Ferdause, Jannatul [1 ]
Momtahena, Sura Jukrup [1 ]
Karim, Rubama [1 ]
Chowdhury, Aditi Paul [1 ]
Hossain, Nowshin Taslima [1 ]
Islam, Md Ariful [1 ]
Bin Habib, Maruf [2 ]
Kadir, A. K. M. Shafiul [3 ]
Haque, Md Ariful [4 ,5 ,6 ]
机构
[1] Ahsania Mission Canc & Gen Hosp, Dhaka, Bangladesh
[2] Ahsania Mission Med Coll, Dept Med, Dhaka, Bangladesh
[3] Quest Bangladesh Biomed Res Ctr, Dhaka, Bangladesh
[4] Atish Dipankar Univ Sci & Technol, Dept Publ Hlth, Dhaka, Bangladesh
[5] Voice Doctors Res Sch, Dhaka, Bangladesh
[6] Kunming Med Univ, Yanan Hosp, Dept Orthopaed Surg, Kunming, Yunnan, Peoples R China
来源
CLINICAL CASE REPORTS | 2024年 / 12卷 / 07期
关键词
anti HER-2 antibody; HER-2-positive breast cancer; Steven Johnson syndrome; toxic epidermal necrolysis; Trastuzumab; STEVENS-JOHNSON SYNDROME; GUIDELINES; MANAGEMENT; COMPLICATIONS; INVOLVEMENT;
D O I
10.1002/ccr3.9103
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Toxic Epidermal Necrolysis (TEN) is a rare, but potentially fatal mucocutaneous reaction, that may occur due to an immunologic response to certain medications. However, TEN triggered by Trastuzumab is extremely rare. Early diagnosis, recognition, and prompt cessation of the offending drugs and initiation of steroid therapy with supportive management are the most important actions for managing TEN. Although rare, it is important to be vigilant about this potential adverse reactions associated with trastuzumab to ensure patient safety and contribute to better outcomes.
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页数:7
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