Magnetic Resonance Imaging and Manganism: A Narrative Review and Laboratory Recommendations

被引：3

作者：

Majewski, Michal ^{[1
]}

Piwko, Karolina ^{[1
]}

Ordak, Michal ^{[1
]}

Muszynska, Elzbieta ^{[2
]}

Nasierowski, Tadeusz ^{[3
]}

Bujalska-Zadrozny, Magdalena ^{[1
]}

机构：

[1] Med Univ Warsaw, Fac Pharm, Dept Pharmacotherapy & Pharmaceut Care, Banacha 1 Str, PL-02097 Warsaw, Poland

[2] Med Univ Bialystok, Dept Med Biol, Mickiewicza 2c Str, PL-15222 Bialystok, Poland

[3] Med Univ Warsaw, Fac Pharm, Dept Psychiat, Nowowiejska 27 Str, PL-00665 Warsaw, Poland

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 10期

关键词：

magnetic resonance imaging; manganese; manganism; INDUCED PARKINSONISM; SIGNAL INTENSITIES; T1; HYPERINTENSITY; MOVEMENT-DISORDER; SMELTING WORKERS; BASAL GANGLIA; EXPOSURE; MRI; TOXICITY; WELDERS;

D O I：

10.3390/jcm13102823

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In recent years, a series of articles has been published concerning magnetic resonance imaging (MRI) studies in a group of patients exposed to manganism, specifically factory workers, welders, and individuals with liver diseases, as well as those abusing home-produced ephedrone. Some potential symptoms of manganese toxicity include motor disturbances, neurocognitive problems, sleep disorders, and psychosocial changes. Despite various publications on MRI research in individuals with an elevated risk of manganism, there is a noticeable absence of a comprehensive review in this field. The detection of the accumulation of manganese in the brain through MRI can confirm the diagnosis and guide appropriate treatment. Due to the high cost of determining manganese ion levels in biological material, an additional aim of the manuscript was to identify simple medical laboratory parameters that, when performed concurrently with MRI, could assist in the diagnosis of manganism. Among these types of parameters are the levels of bilirubin, magnesium, liver enzymes, creatinine, hemoglobin, and hematocrit.

引用

页数：16

共 112 条

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