Beta-blockers for the treatment of infantile haemangiomas in premature infants

被引:0
作者
Ling, Lynn Chua Ting [1 ]
Aan, Mark Koh Jean [1 ]
机构
[1] KK Women & Childrens Hosp, Dept Pediat, Dermatol, 100 Bukit Timah Rd, Singapore 229899, Singapore
关键词
beta-blockers; infantile haemangioma; propranolol; timolol; PROPRANOLOL; EFFICACY; SAFETY;
D O I
10.1111/ajd.14338
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Beta-blockers have been established as a treatment of infantile haemangiomas (IH) since its serendipitous discovery for use in IH in 2008. However, data on the safety of these beta-blockers for use in IH in preterm infants are scarce. A retrospective study was performed to review the safety of oral propranolol and topical timolol in the treatment of IH in a cohort of preterm infants treated at our tertiary paediatric hospital. It was observed that there was an increased risk of adverse events amongst the preterm infants with chronic lung disease, retinopathy of prematurity and gastroesophageal reflux, when treated with oral propranolol.
引用
收藏
页码:e194 / e197
页数:4
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