A novel platform of diversified payloads to drive ADC innovation

被引:1
|
作者
Orsini, Paolo
Salsa, Matteo
Rizzi, Simona
Cucchi, Ulisse
Faiardi, Daniela
Burocchi, Alessia
Ciavolella, Antonella
Lupi, Rosita
Gasparri, Fabio
Valsasina, Barbara
机构
关键词
D O I
10.1158/1538-7445.AM2024-5805
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5805
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Discovery platform for potent ADC payloads from marine sources
    Macherla, V
    Pociute, E.
    Cardenas, G.
    Stout, P.
    Mayer, T.
    Beverage, J.
    Esquenazi, E.
    PLANTA MEDICA, 2015, 81 (11) : 912 - 912
  • [2] Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads
    Leverett, Carolyn A.
    Sukuru, Sai Chetan K.
    Vetelino, Beth C.
    Musto, Sylvia
    Parris, Kevin
    Pandit, Jayvardhan
    Loganzo, Frank
    Varghese, Alison H.
    Bai, Guoyun
    Liu, Bin
    Liu, Dingguo
    Hudson, Sarah
    Doppalapudi, Venkata Ramana
    Stock, Joseph
    O'Donnell, Christopher J.
    Subramanyam, Chakrapani
    ACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (11): : 999 - 1004
  • [3] Challenges and opportunities in the synthesis of ADC payloads
    Goundry, William
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [4] Delivery of potent cytotoxins as ADC payloads
    Verma, Vishal
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
  • [5] Make platform innovation drive enterprise growth
    Meyer, MH
    Mugge, PC
    RESEARCH-TECHNOLOGY MANAGEMENT, 2001, 44 (01) : 25 - 39
  • [6] Towards new cryptophycins as promising payloads for ADC
    Brun, Marie-Priscille
    Bouchard, Herve
    Clerc, Francois
    Zhang, Jidong
    Abecassis, Pierre-Yves
    Amara, Celine
    Beys, Eric
    Efremenko, Florence
    Nicolazzi, Celine
    Pascual, Marie-Helene
    Pasquier, Olivier
    Krick, Alain
    Berne, Pierre-Francois
    Gauzy, Laurence
    Karst, Nathalie
    Huille, Sylvain
    Henry, Christophe
    Lefebvre, Anne-Marie
    Sassoon, Ingrid
    CANCER RESEARCH, 2016, 76
  • [7] Novel oncolytic vaccinia virus platform for systemic delivery of immunotherapeutic payloads
    Bell, John C.
    Pelin, Adrian
    Huh, Michael
    Tang, Matthew
    Le Boeuf, Fabrice
    Keller, Brian
    Duong, Jessie
    Clark-Knowles, Katherine
    Petryk, Julia
    Jennings, Victoria A.
    Melcher, Alan
    Crupi, Mathieu
    Pikor, Larissa
    Breitbach, Caroline
    Bernstein, Steven
    Burgess, Michael
    CANCER IMMUNOLOGY RESEARCH, 2019, 7 (02)
  • [8] Building a powerful ADCs discovery and development platform with novel dolastatin/auristatin payloads
    Hu, Shanghui
    Zhao, Lucy X.
    Liu, Xu
    Li, Chao
    Hu, Wei
    Wang, Zunrong
    Tian, Xufang
    CANCER RESEARCH, 2014, 74 (19)
  • [9] Development of an HPLC method for the assessment of hydrophobicity of ADC payloads
    Pysz, Ilona
    Jackson, Paul J.
    Rahman, Khondaker M.
    Thurston, David E.
    CANCER RESEARCH, 2018, 78 (13)
  • [10] Novel ADC platform delivers promising in vivo activity and safety
    Liu, Haidong
    Qi, Wenke
    Wang, Lei
    Wang, Guobao
    Chen, Xinyue
    Gavrilyuk, Julia
    Han, Tae
    Zhao, Baiteng
    Shang, Xiao
    CANCER RESEARCH, 2022, 82 (12)