Individual treatment selection for patients with post-traumatic stress disorder: External validation of a personalised advantage index

被引：3

作者：

Tait, James ^{[1
]}

Kellett, Stephen ^{[2
]}

Saxon, David ^{[3
]}

Deisenhofer, Anne-Katharina ^{[4
]}

Lutz, Wolfgang ^{[4
]}

Barkham, Michael ^{[3
]}

Delgadillo, Jaime ^{[3
]}

机构：

[1] Univ Sheffield, Sch Psychol, ICOSS Bldg,219 Portobello, Sheffield S1 4DP, England

[2] RDaSH NHS Fdn Trust, Grounded Res, Doncaster, England

[3] Univ Sheffield, Sch Psychol, Clin & Appl Psychol Unit, Sheffield, England

[4] Univ Trier, Dept Psychol, Clin Psychol & Psychotherapy, Trier, Germany

来源：

PSYCHOTHERAPY RESEARCH | 2024年

关键词：

psychotherapy; posttraumatic stress disorder; mental health services; machine learning; clinical models; external validity; COGNITIVE-BEHAVIORAL THERAPY; PREDICTIVE MODELS; PROPENSITY SCORE; DEPRESSION; SAMPLE; SIZE; ANXIETY; WORK; PTSD; BIAS;

D O I：

10.1080/10503307.2024.2360449

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

ObjectiveTo test the predictive accuracy and generalisability of a personalised advantage index (PAI) model designed to support treatment selection for Post-Traumatic Stress Disorder (PTSD).MethodA PAI model developed by Deisenhofer et al. (2018) was used to predict treatment outcomes in a statistically independent dataset including archival records for N = 152 patients with PSTD who accessed either trauma-focussed cognitive behavioural therapy or eye movement desensitisation and reprocessing in routine care. Outcomes were compared between patients who received their PAI-indicated optimal treatment versus those who received their suboptimal treatment.ResultsThe model did not yield treatment specific predictions and patients who had received their PAI-indicated optimal treatment did not have better treatment outcomes in this external validation sample.ConclusionThis PAI model did not generalise to an external validation sample.

引用

页数：14