Continuous flow ring-opening polymerization and ring-opening metathesis polymerization

被引：5

作者：

Liu, Yihuan ^{[1
]}

Ou, Shi ^{[1
]}

Wu, Jiaqi ^{[1
]}

Zhao, Rongji ^{[1
]}

Hou, Ruixiang ^{[2
]}

Li, Xiaomin ^{[2
]}

Sun, Yongxiang ^{[3
]}

Li, Yuguang ^{[4
]}

Hu, Xin ^{[5
]}

Zhu, Ning ^{[1
]}

Guo, Kai ^{[1
,6
]}

机构：

[1] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, Nanjing 211816, Peoples R China

[2] Sinopec, Beijing Res Inst Chem Ind, Beijing 100013, Peoples R China

[3] Sumec Text Technol & Ind Co LTD, Nanjing 210019, Peoples R China

[4] Inst Nanjing Adv Biomat & Proc Equipment, Nanjing 211299, Peoples R China

[5] Nanjing Tech Univ, Coll Mat Sci & Engn, Nanjing 211816, Peoples R China

[6] Nanjing Tech Univ, State Key Lab Mat Oriented Chem Engn, Nanjing 211816, Peoples R China

来源：

EUROPEAN POLYMER JOURNAL | 2024年 / 216卷

关键词：

Continuous flow; Ring-opening polymerization; Ring-opening metathesis polymerization; Polymer synthesis; MICROWAVE-ASSISTED POLYMERIZATIONS; OLEFIN METATHESIS; ENZYMATIC-SYNTHESIS; SYNTHETIC APPROACH; CARBON-DIOXIDE; SCALE-UP; CATALYSTS; POLY(EPSILON-CAPROLACTONE); 2-ETHYL-2-OXAZOLINE; BOTTLEBRUSH;

D O I：

10.1016/j.eurpolymj.2024.113288

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The combination of microflow technology and ring-opening polymerization (ROP) or ring-opening metathesis polymerization (ROMP) has been proved to be an effective method for well-defined polymers. Microreactorbased ROP or ROMP enables the distinguished advantages over traditional batchwise reactor, including faster apparent polymerization rate, higher conversion and chemoselectivity, narrower dispersity, easier scale-up and the ability to telescope several synthetic steps into a single system. In this view, ROP of a variety of cyclic monomers was highlighted, including lactone, lactide, epoxide, 2-oxazoline, N-carboxyanhydride and cyclic phosphoester. ROMP in the context of flow chemistry was introduced. Challenges and opportunities are proposed for the future development of continuous flow ROP and ROMP.

引用

页数：17

共 164 条

[1] Polylactones synthesis by enzymatic ring opening polymerization in flow [J].

Adhami, Wissal ;

Bakkour, Youssef ;

Rolando, Christian .

POLYMER, 2021, 230

[2] Recent developments in ring opening polymerization of lactones for biomedical applications [J].

Albertsson, AC ;

Varma, IK .

BIOMACROMOLECULES, 2003, 4 (06) :1466-1486

[3] Grubbs' Ruthenium-Carbenes Beyond the Metathesis Reaction: Less Conventional Non-Metathetic Utility [J].

Alcaide, Benito ;

Almendros, Pedro ;

Luna, Amparo .

CHEMICAL REVIEWS, 2009, 109 (08) :3817-3858

[4] Anionic flow polymerizations toward functional polyphosphoesters in microreactors: Polymerization and UV-modification [J].

Baeten, Evelien ;

Vanslambrouck, Stephanie ;

Jerome, Christine ;

Lecomte, Philippe ;

Junkers, Tanja .

EUROPEAN POLYMER JOURNAL, 2016, 80 :208-218

[5] Continuous poly(2-oxazoline) triblock copolymer synthesis in a microfluidic reactor cascade [J].

Baeten, Evelien ;

Verbraeken, Bart ;

Hoogenboom, Richard ;

Junkers, Tanja .

CHEMICAL COMMUNICATIONS, 2015, 51 (58) :11701-11704

[6] One-pot multifunctional polyesters by continuous flow organocatalysed ring-opening polymerisation for targeted and tunable materials design [J].

Bakkali-Hassani, Camille ;

Hooker, Jordan P. ;

Voorter, Pieter-Jan ;

Rubens, Maarten ;

Cameron, Neil R. ;

Junkers, Tanja .

POLYMER CHEMISTRY, 2022, 13 (10) :1387-1393

[7] Poly(lactic Acid): A Versatile Biobased Polymer for the Future with Multifunctional Properties-From Monomer Synthesis, Polymerization Techniques and Molecular Weight Increase to PLA Applications [J].

Balla, Evangelia ;

Daniilidis, Vasileios ;

Karlioti, Georgia ;

Kalamas, Theocharis ;

Stefanidou, Myrika ;

Bikiaris, Nikolaos D. ;

Vlachopoulos, Antonios ;

Koumentakou, Ioanna ;

Bikiaris, Dimitrios N. .

POLYMERS, 2021, 13 (11)

[8] Polyether Synthesis by Bulk Self-Condensation of Diols Catalyzed by Non-Eutectic Acid-Base Organocatalysts [J].

Basterretxea, Andere ;

Gabirondo, Elena ;

Jehanno, Coralie ;

Zhu, Haijin ;

Flores, Irma ;

Mueller, Alejandro J. ;

Etxeberria, Agustin ;

Mecerreyes, David ;

Coulembier, Olivier ;

Sardon, Haritz .

ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2019, 7 (04) :4103-4111

[9] A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry [J].

Baumann, Marcus ;

Moody, Thomas S. ;

Smyth, Megan ;

Wharry, Scott .

ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2020, 24 (10) :1802-1813

[10] Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups [J].

Becker, Greta ;

Wurm, Frederik R. .

CHEMICAL SOCIETY REVIEWS, 2018, 47 (20) :7739-7782

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