Dual-mode detection of antibiotic drugs using ytterbium molybdate/porous carbon nanocomposite

被引:2
作者
Babulal, Sivakumar Musuvadhi [1 ]
Alagumalai, Krishnapandi [2 ]
Sivakumar, Mani [3 ]
Chen, Shen Ming [1 ]
Kim, Seong-Cheol [2 ]
Bharathi, Arumugam [2 ]
Babulal, Lakshmipriya Musuvadhi [4 ]
Karuppiah, Chelladurai [4 ]
Alothman, Asma A. [5 ]
Aldosari, Eman [5 ]
机构
[1] Natl Taipei Univ Technol, Coll Engn, Dept Chem Engn & Biotechnol, Taipei 10608, Taiwan
[2] Yeungnam Univ, Sch Chem Engn, Gyongsan 38541, South Korea
[3] Saveetha Univ, Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, Gen Pathol, Chennai 600077, Tamil Nadu, India
[4] Ming Chi Univ Technol, Battery Res Ctr Green Energy, New Taipei 24301, Taiwan
[5] King Saud Univ, Coll Sci, Chem Dept, Riyadh 11451, Saudi Arabia
来源
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | 2024年 / 12卷 / 02期
基金
新加坡国家研究基金会;
关键词
YbMO/PC; Metronidazole; Real-time approach; UV-vis spectrascopy analysis; Electrochemical sensor; ELECTROCHEMICAL SENSOR; GRAPHENE OXIDE; DEGRADATION; PERFORMANCE; CATALYST; METRONIDAZOLE; NANOPARTICLES; NANOSHEETS; NANOTUBES; COMPOSITE;
D O I
10.1016/j.jece.2024.112331
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Monitoring the levels of metronidazole (MTZ) is crucial to ensure the desired therapeutic effectiveness and to prevent potential harm to patients. However, MTZ exhibits concentration -dependent antimicrobial activity and has a narrow therapeutic range. In this study, "one stone two mango" strategy was influenced for the electrochemical and UV-vis spectroscopy detection of antibiotic residues of MTZ. The successfully synthesized ytterbium molybdate nano petals (YbMO) with porous carbon (PC) nanocomposite (NC) using ultrasonication method. The YbMO/PC NC, as well as other modified electrodes, were identified and targeted as molecules using natural pH as the probe to indicate current intensity. Also, examined the morphology and physicochemical properties of the synthesized materials. Furthermore, conducted cycling voltammetry (CV) and linear sweep voltammetry (LSV) on the modified electrodes to model MTZ analytes. Among them, the YbMO/PC NC/GCE exhibited larger reduction peak current and lower potential compared to other modified electrodes due to the synergistic effect between YbMO and PC, resulting in effective detection of MTZ. The YbMO/PC NC/GCE demonstrated exceptional sensitivity (3.28 mu A mu M-1 cm -2), a wide linear range (0.01-10.61 and 20.61-1630.61 mu M), and a remarkably low detection limit (LOD: 0.006 mu M). The proposed YbMO/PC NC/GCE exhibits the successfully analyzed MTZ in serum (101%), urine (97.9%), tablets (99.15%), lake (99.1%), and river water (99.8%). On the other hand, a UV-vis spectrometric method was employed to detect MTZ. The results showed a wide linear range (0.05-57.2 mu M) and an impressive LOD (70 nM). These results are attributed to the heightened sensitivity, selectivity, repeatability, and durability of the sensor.
引用
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页数:10
相关论文
共 59 条
  • [1] Simultaneous Determination of Diloxanide Furoate and Metronidazole in Presence of Diloxanide Furoate Degradation Products
    Abbas, Samah S.
    Wagieh, Nour E.
    Abdelkawy, Mohamed
    Abdelrahman, Maha M.
    [J]. JOURNAL OF AOAC INTERNATIONAL, 2011, 94 (05) : 1427 - 1439
  • [2] Rational synthesis of rare-earth lanthanum molybdate covered reduced graphene oxide nanocomposites for the voltammetric detection of Moxifloxacin hydrochloride
    Akilarasan, Muthumariappan
    Tamilalagan, Elayappan
    Chen, Shen-Ming
    Maheshwaran, Selvarasu
    Fan, Chih-Hsuan
    Habila, Mohamed A.
    Sillanpaa, Mika
    [J]. BIOELECTROCHEMISTRY, 2022, 146
  • [3] [Anonymous], Low Temperature Synthesis and Characterization of Flower Like Ytterbium Molybdate Nanopowders and Investigate Supercapacitor Properties, V11, P1087
  • [4] Self assembled three dimensional ?-Cu2V2O7 hierarchical flower decorated porous carbon: An efficient electrocatalyst for flutamide detection in biological and environmental samples
    Babulal, Sivakumar Musuvadhi
    Anupriya, Jeyaraman
    Chen, Shen Ming
    [J]. CHEMOSPHERE, 2022, 303
  • [5] Rational construction of novel rose petals-like yttrium molybdate nanosheets: A Janus catalyst for the detection and degradation of cardioselective β-blocker agent acebutolol
    Chen, Tse-Wei
    Kumar, Jeyaraj Vinoth
    Chen, Shen-Ming
    Mutharani, Bhuvanenthiran
    Karthik, Raj
    Nagarajan, E. R.
    Muthuraj, Velluchamy
    [J]. CHEMICAL ENGINEERING JOURNAL, 2019, 359 : 1472 - 1485
  • [6] Sensitive sensing platform based on NiO and NiO-Ni nanoparticles for electrochemical determination of Metronidazole
    Darbandi, Masih
    Mohajer, Mahsa Fathalipour
    Eynollahi, Mahsa
    Asadpour-Zeynali, Karim
    [J]. CHEMICAL PHYSICS, 2022, 560
  • [7] Development of amine-based transition metal MOFs as efficient electrochemical sensors for the detection of chloramphenicol in food and pharmaceutical samples
    Dhayanithi, Chettipalayam Arunasalam
    Palpandi, Karuppaiya
    Raman, Natarajan
    Babu, Sundaram Ganesh
    [J]. ELECTROCHIMICA ACTA, 2023, 470
  • [8] Plasmonic hot electron transfer-induced multicolor MoO3-x-based chromogenic system for visual and colorimetric determination of silver(I)
    Du, Jiayan
    Wang, Junren
    Deng, Yuequan
    He, Yi
    [J]. MICROCHIMICA ACTA, 2020, 187 (02)
  • [9] Materials framework based bio/sensors for the detection of ornidazole and metronidazole antibiotics in environment and foodstuffs
    Ettadili, F. E.
    Azriouil, M.
    Matrouf, M.
    Alaoui, O. Tahiri
    Laghrib, F.
    Farahi, A.
    Bakasse, M.
    Saqrane, S.
    Lahrich, S.
    El Mhammedi, M. A.
    [J]. INORGANIC CHEMISTRY COMMUNICATIONS, 2022, 140
  • [10] One step synthesis cadmium sulphide/reduced graphene oxide sandwiched film modified electrode for simultaneous electrochemical determination of hydroquinone, catechol and resorcinol
    Hu, Shirong
    Zhang, Wuxiang
    Zheng, Jianzhong
    Shi, Jiangu
    Lin, Zhongqiu
    Zhong, Ling
    Cai, Guixiang
    Wei, Chan
    Zhang, Hanqiang
    Hao, Aiyou
    [J]. RSC ADVANCES, 2015, 5 (24): : 18615 - 18621